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Table 3 Mean changes in desmosine and Isodesmoeine after two months of Tiotropium therapy

From: The effect of tiotropium therapy on markers of elastin degradation in COPD

BODY FLUID

N

LEVELS (mean ± SD)

P VALUE

  

AT BASELINE

AT 2 MONTHS

 

Plasma ng/ml

12

0.62 ± 0.12

0.43 ± 0.10

0.0037

Urine (free/total %)

12

45.96 ± 8.11

38.37 ± 4.43

0.0044

Sputum ng/ml

12

0.39 ± 0.26

0.13 ± 0.02

0.0035

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Respiratory Research

ISSN: 1465-993X

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