From: Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers
Category | Probe set ID | Gene symbol | Gene title | Nonsmokers % present2 | Healthy smokers % present | Smokers/non-smokers (fold-change) | p value |
---|---|---|---|---|---|---|---|
Glutathione metabolism | 202923_s_at | GCLC | glutamate-cysteine ligase, catalytic subunit | 100 | 100 | 1.67 | 0.007 |
Redox balance | No smoking responsive genes in this category in the alveolar macrophages | ||||||
Catalase/SOD | 216841_s_at | SOD2 | superoxide dismutase 2 | 100 | 100 | -2.06 | 0.006 |
Oxidant scavengers | No smoking responsive genes in this category in the alveolar macrophages | ||||||
Pentose phosphate cycle | 213093_at | PRKCA | protein kinase C, alpha | 95 | 100 | 1.86 | 0.037 |
Xenobiotic metabolism | 205939_at | CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | 58 | 10 | -3.69 | 0.030 |
Bilirubin related | 209236_at | SLC23A2solute carrier family 23, member 2 | Â | 89 | 100 | 1.50 | 0.038 |
Ascorbic acid related | No smoking responsive genes in this category in the alveolar macrophages | ||||||
Production of free radicals | No smoking responsive genes in this category in the alveolar macrophages |