Skip to content

Advertisement

Articles

Page 7 of 50

  1. Content type: Review

    Since the initial discovery of the oncogenic activity of WNT ligands our understanding of the complex roles for WNT signaling pathways in lung cancers has increased substantially. In the current review, the va...

    Authors: Judit Rapp, Luca Jaromi, Krisztian Kvell, Gyorgy Miskei and Judit E. Pongracz

    Citation: Respiratory Research 2017 18:167

    Published on:

  2. Content type: Research

    Extracellular histones were recently identified as an inflammatory mediator involved in the pathogenesis of various organ injuries. This study aimed to examine extracellular histone levels and their clinical i...

    Authors: Xin Lv, Tao Wen, Jiong Song, Dong Xie, Liang Wu, Xuemei Jiang, Ping Jiang and Zongmei Wen

    Citation: Respiratory Research 2017 18:165

    Published on:

  3. Content type: Research

    Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines which participate in clearing viral infections. Cigarette smoke (CS)...

    Authors: Xiaoqiu Wang, Wenxin Wu, Wei Zhang, J. Leland Booth, Elizabeth S. Duggan, Lili Tian, Sunil More, Yan D. Zhao, Ravindranauth N. Sawh, Lin Liu, Ming-Hui Zou and Jordan P. Metcalf

    Citation: Respiratory Research 2017 18:166

    Published on:

  4. Content type: Research

    Induced and spontaneous sputum are used to evaluate the airways microbiota. Whether the sputum types can be used interchangeably in microbiota research is unknown. Our aim was to compare microbiota in induced ...

    Authors: Solveig Tangedal, Marianne Aanerud, Rune Grønseth, Christine Drengenes, Harald G. Wiker, Per S. Bakke and Tomas M. Eagan

    Citation: Respiratory Research 2017 18:164

    Published on:

  5. Content type: Research

    Tracheal obstruction resulting from expiratory tracheal deformation has been associated with respiratory symptoms and severe airway exacerbations. In chronic obstructive pulmonary disease (COPD), acute exacerb...

    Authors: Paul Leong, Anne Tran, Jhanavi Rangaswamy, Laurence E. Ruane, Michael W. Fernando, Martin I. MacDonald, Kenneth K. Lau and Philip G. Bardin

    Citation: Respiratory Research 2017 18:163

    Published on:

  6. Content type: Research

    COPD prevalence is highly variable and geographical altitude has been linked to it, yet with conflicting results. We aimed to investigate this association, considering well known risk factors.

    Authors: Andreas Horner, Joan B. Soriano, Milo A. Puhan, Michael Studnicka, Bernhard Kaiser, Lowie E. G. W. Vanfleteren, Louisa Gnatiuc, Peter Burney, Marc Miravitlles, Francisco García-Rio, Julio Ancochea, Ana M. Menezes, Rogelio Perez-Padilla, Maria Montes de Oca, Carlos A. Torres-Duque, Andres Caballero…

    Citation: Respiratory Research 2017 18:162

    Published on:

  7. Content type: Research

    Autoimmune serologies are often obtained in the initial evaluation of uncharacterized interstitial lung disease (ILD). Whether this practice is helpful in delineating connective-tissue disease related ILD (CTD...

    Authors: Mohammad Alsumrain, Federica De Giacomi, Shireen Mirza and Teng Moua

    Citation: Respiratory Research 2017 18:161

    Published on:

  8. Content type: Research

    Cigarette smoking has been associated with the risk of idiopathic pulmonary fibrosis (IPF). Certain comorbidities have been associated with reduced survival although some studies have indicated that current sm...

    Authors: Miia Kärkkäinen, Hannu-Pekka Kettunen, Hanna Nurmi, Tuomas Selander, Minna Purokivi and Riitta Kaarteenaho

    Citation: Respiratory Research 2017 18:160

    Published on:

  9. Content type: Research

    Increased interferon gamma (IFNγ) release occurs in Chronic Obstructive Pulmonary Disease (COPD) lungs. IFNγ supports optimal viral clearance, but if dysregulated could increase lung tissue destruction.

    Authors: Emmanuel Briend, G. John Ferguson, Michiko Mori, Gautam Damera, Katherine Stephenson, Natasha A. Karp, Sanjay Sethi, Christine K. Ward, Matthew A. Sleeman, Jonas S. Erjefält and Donna K. Finch

    Citation: Respiratory Research 2017 18:159

    Published on:

  10. Content type: Erratum

    Authors: Colin Reisner, Leonardo M. Fabbri, Edward M. Kerwin, Charles Fogarty, Selwyn Spangenthal, Klaus F. Rabe, Gary T. Ferguson, Fernando J. Martinez, James F. Donohue, Patrick Darken, Earl St. Rose, Chad Orevillo, Shannon Strom, Tracy Fischer, Michael Golden and Sarvajna Dwivedi

    Citation: Respiratory Research 2017 18:158

    Published on:

    The original article was published in Respiratory Research 2017 18:8

  11. Content type: Research

    Symptoms of chronic obstructive pulmonary disease may vary throughout the day and it is important that therapeutic approaches provide 24-h symptom control. We report the results of two phase IIIb crossover stu...

    Authors: Colin Reisner, Gregory Gottschlich, Faisal Fakih, Andras Koser, James Krainson, Luis Delacruz, Samir Arora, Gregory Feldman, Krishna Pudi, Shahid Siddiqui, Chad Orevillo, Andrea Maes, Earl St. Rose and Ubaldo Martin

    Citation: Respiratory Research 2017 18:157

    Published on:

  12. Content type: Review

    Airway remodelling is an important feature of asthma pathogenesis. A key structural change inherent in airway remodelling is increased airway smooth muscle mass. There is emerging evidence to suggest that the ...

    Authors: Brittany Salter, Cara Pray, Katherine Radford, James G. Martin and Parameswaran Nair

    Citation: Respiratory Research 2017 18:156

    Published on:

  13. Content type: Research

    Chronic obstructive pulmonary disease (COPD) is an obstinate pulmonary disease, causing irreversible alveoli collapse and increasing the risk for cardiovascular disease. Accumulating evidence has shown that th...

    Authors: Yong Du, Yi Ding, Xuru Chen, Zhoufang Mei, Heyuan Ding, Yi Wu and Zhijun Jie

    Citation: Respiratory Research 2017 18:155

    Published on:

  14. Content type: Review

    Mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1) is a protein with anti-inflammatory properties and the archetypal member of the dual-specificity phosphatases (DUSPs) family that have emerged over...

    Authors: Seyed M. Moosavi, Pavan Prabhala and Alaina J. Ammit

    Citation: Respiratory Research 2017 18:154

    Published on:

  15. Content type: Research

    Failure to attain peak lung function by early adulthood is a risk factor for chronic lung diseases. Previously, we reported that C3H/HeJ mice have about twice total lung capacity (TLC) compared to JF1/MsJ mice...

    Authors: Leema George, Ankita Mitra, Tania A. Thimraj, Martin Irmler, Sangeetha Vishweswaraiah, Lars Lunding, Dorothea Hühn, Alicia Madurga, Johannes Beckers, Heinz Fehrenbach, Swapna Upadhyay, Holger Schulz, George D. Leikauf and Koustav Ganguly

    Citation: Respiratory Research 2017 18:152

    Published on:

  16. Content type: Research

    Interleukin-1 receptor 1 (IL-1R1) inhibition is a potential strategy for treating patients with chronic obstructive pulmonary disease (COPD). MEDI8968, a fully human monoclonal antibody, binds selectively to I...

    Authors: Peter M. A. Calverley, Sanjay Sethi, Michelle Dawson, Christine K. Ward, Donna K. Finch, Mark Penney, Paul Newbold and René van der Merwe

    Citation: Respiratory Research 2017 18:153

    Published on:

  17. Content type: Research

    Alveolar type 2 (AT2) cells play important roles in maintaining adult lung homeostasis. AT2 cells isolated from the lung have revealed the cell-specific functions of AT2 cells. Comprehensive molecular and tran...

    Authors: Koichi Hasegawa, Atsuyasu Sato, Kazuya Tanimura, Kiyoshi Uemasu, Yoko Hamakawa, Yoshinori Fuseya, Susumu Sato, Shigeo Muro and Toyohiro Hirai

    Citation: Respiratory Research 2017 18:150

    Published on:

  18. Content type: Review

    The role of differential cytology patterns in peripheral blood and bronchoalveolar lavage samples is increasingly investigated as a potential adjunct to diagnose acute and chronic allograft dysfunction after l...

    Authors: Nicole E. Speck, Macé M. Schuurmans, Christian Benden, Cécile A. Robinson and Lars C. Huber

    Citation: Respiratory Research 2017 18:151

    Published on:

  19. Content type: Research

    Diffuse alveolar damage (DAD), which is the histological surrogate for acute respiratory distress syndrome (ARDS), has a multifactorial aetiology. Therefore it is possible that the immunopathology differs amon...

    Authors: Monique Buttignol, Ruy Camargo Pires-Neto, Renata Calciolari Rossi e Silva, Marina Ballarin Albino, Marisa Dolhnikoff and Thais Mauad

    Citation: Respiratory Research 2017 18:147

    Published on:

  20. Content type: Review

    Omics approaches are high-throughput unbiased technologies that provide snapshots of various aspects of biological systems and include: 1) genomics, the measure of DNA variation; 2) transcriptomics, the measur...

    Authors: Mengyuan Kan, Maya Shumyatcher and Blanca E. Himes

    Citation: Respiratory Research 2017 18:149

    Published on:

  21. Content type: Letter to the Editor

    The Global Initiative for Asthma (GINA) guidelines do not specify a bronchodilator range for bronchodilator response (BDR) testing and simply recommend a salbutamol dose of 200 to 400 μg. We determined the osc...

    Authors: Dong Keon Yon, Hye Mi Jee, Eun Kyo Ha, Seung Jin Lee, Young-Ho Jung, Kyung Suk Lee and Man Yong Han

    Citation: Respiratory Research 2017 18:148

    Published on:

  22. Content type: Research

    Methacholine dose-response curves illustrate pharmacologic bronchoprotection against methacholine-induced airway hyperresponsiveness and can be used to quantitate changes in airway sensitivity (position), reac...

    Authors: Christianne M. Blais, Beth E. Davis and Donald W. Cockcroft

    Citation: Respiratory Research 2017 18:146

    Published on:

  23. Content type: Research

    Muscarinic-receptor antagonists and β-adrenoceptor agonists are used, alone or in combination, as first-line treatment for chronic obstructive pulmonary disease. Both drugs decrease airway smooth muscle tone b...

    Authors: Michele Baroffio, Giovanni Barisione and Vito Brusasco

    Citation: Respiratory Research 2017 18:145

    Published on:

  24. Content type: Research

    Ambient particulate matter exposure has been shown to increase the risks of respiratory diseases. However, the role of the lung microbiome and the immune response to inhaled particulate matter are largely unex...

    Authors: Naijian Li, Fang He, Baoling Liao, Yuming Zhou, Bing Li and Pixin Ran

    Citation: Respiratory Research 2017 18:143

    Published on:

  25. Content type: Research

    Non-invasive ventilation (NIV) improves survival and quality of life in amyotrophic lateral sclerosis (ALS) patients. The timing of referral to a home ventilation service (HVS), which is in part based on respi...

    Authors: T. B. M. Tilanus, J. T. Groothuis, J. M. C. TenBroek-Pastoor, T. B. Feuth, Y. F. Heijdra, J. P. L. Slenders, J. Doorduin, B. G. Van Engelen, M. J. Kampelmacher and J. Raaphorst

    Citation: Respiratory Research 2017 18:144

    Published on:

  26. Content type: Research

    Studies aiming to assess genetic susceptibility for impaired lung function levels upon exposure to environmental tobacco smoke (ETS) have thus far focused on candidate-genes selected based on a-priori knowledg...

    Authors: K. de Jong, J.M. Vonk, M. Imboden, L. Lahousse, A. Hofman, G.G. Brusselle, N.M. Probst-Hensch, D.S. Postma and H.M. Boezen

    Citation: Respiratory Research 2017 18:142

    Published on:

  27. Content type: Research

    Dual bronchodilation combining a long-acting β2-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) is the preferred choice of treatment recommended by the Global Initiative for Chronic Obstructive Lung...

    Authors: Claus F. Vogelmeier, Mina Gaga, Maryam Aalamian-Mattheis, Timm Greulich, Jose M. Marin, Walter Castellani, Vincent Ninane, Stephen Lane, Xavier Nunez, Francesco Patalano, Andreas Clemens and Konstantinos Kostikas

    Citation: Respiratory Research 2017 18:140

    Published on:

  28. Content type: Research

    Interstitial lung disease (ILD) can be a severe extra-articular disease manifestation in Rheumatoid Arthritis (RA). A potential role of fibrocytes in RA associated ILD (RA-ILD) has not previously been describe...

    Authors: Søren Andreas Just, Hanne Lindegaard, Eva Kildall Hejbøl, Jesper Rømhild Davidsen, Niels Bjerring, Søren Werner Karlskov Hansen, Henrik Daa Schrøder, Inger Marie Jensen Hansen, Torben Barington and Christian Nielsen

    Citation: Respiratory Research 2017 18:141

    Published on:

  29. Content type: Research

    The INSIGHTS-IPF registry provides one of the largest data sets of clinical data and self-reported patient related outcomes including health related quality of life (QoL) on patients with idiopathic pulmonary ...

    Authors: Michael Kreuter, Jeff Swigris, David Pittrow, Silke Geier, Jens Klotsche, Antje Prasse, Hubert Wirtz, Dirk Koschel, Stefan Andreas, Martin Claussen, Christian Grohé, Henrike Wilkens, Lars Hagmeyer, Dirk Skowasch, Joachim F Meyer, Joachim Kirschner…

    Citation: Respiratory Research 2017 18:139

    Published on:

  30. Content type: Research

    Mesenchymal stem cells (MSCs) attenuate lung injury in experimental models of bronchopulmonary dysplasia (BPD). Stromal derived factor-1 (SDF-1), a chemokine secreted by MSCs, modulates angiogenesis and stem c...

    Authors: Joel Reiter, Shelley Drummond, Ibrahim Sammour, Jian Huang, Victoria Florea, Polliana Dornas, Joshua M. Hare, Claudia O. Rodrigues and Karen C. Young

    Citation: Respiratory Research 2017 18:137

    Published on:

  31. Content type: Research

    Various factors may affect lung function at different stages in life. Since investigations that simultaneously consider several factors are rare, we examined the relative importance of early life, current envi...

    Authors: Agnes Luzak, Elaine Fuertes, Claudia Flexeder, Marie Standl, Andrea von Berg, Dietrich Berdel, Sibylle Koletzko, Joachim Heinrich, Dennis Nowak and Holger Schulz

    Citation: Respiratory Research 2017 18:138

    Published on:

  32. Content type: Research

    Inhibitors of mTOR, such as sirolimus, have been shown to induce thymus involution and inflammatory lung disease in mice. The latter effect supports the role of this serine/threonine kinase in ameliorating lun...

    Authors: Ahmed R. Alsuwaidi, Junu A. George, Saeeda Almarzooqi, Stacey M. Hartwig, Steven M. Varga and Abdul-Kader Souid

    Citation: Respiratory Research 2017 18:136

    Published on:

  33. Content type: Research

    Several studies have investigated the prevalence and risk factors of insomnia in subjects with obstructive sleep apnea syndrome. However, few studies have investigated the prevalence and risk factors for obstr...

    Authors: Matthieu Hein, Jean-Pol Lanquart, Gwénolé Loas, Philippe Hubain and Paul Linkowski

    Citation: Respiratory Research 2017 18:135

    Published on:

  34. Content type: Research

    Bronchial thermoplasty (BT) is an emerging bronchoscopic intervention for the treatment of severe asthma. The predictive factors for clinical response to BT are unknown. We examined the relationship between th...

    Authors: David Langton, Joy Sha, Alvin Ing, David Fielding, Francis Thien and Virginia Plummer

    Citation: Respiratory Research 2017 18:134

    Published on:

  35. Content type: Letter to the Editor

    The concept of asthma inflammatory phenotypes has proved to be important in predicting response to inhaled corticosteroids. Induced sputum, which has been pivotal in the development of the concept of inflammat...

    Authors: Sophie F. Demarche, Florence N. Schleich, Virginie A. Paulus, Monique A. Henket, Thierry J. Van Hees and Renaud E. Louis

    Citation: Respiratory Research 2017 18:133

    Published on:

  36. Content type: Research

    Resident stem and progenitor cells have been identified in the lung over the last decade, but isolation and culture of these cells remains a challenge. Thus, although these lung stem and progenitor cells provi...

    Authors: Phuong-Uyen C. Dinh, Jhon Cores, M. Taylor Hensley, Adam C. Vandergriff, Junnan Tang, Tyler A. Allen, Thomas G. Caranasos, Kenneth B. Adler, Leonard J. Lobo and Ke Cheng

    Citation: Respiratory Research 2017 18:132

    Published on:

  37. Content type: Research

    Obstructive sleep apnea is characterized by intermittent hypoxia and hypercapnia. CO2 production, transport and elimination are influenced by the carbonic anhydrase enzyme. We hypothesized that elevated standard ...

    Authors: Davoud Eskandari, Ding Zou, Ludger Grote, Hartmut Schneider, Thomas Penzel and Jan Hedner

    Citation: Respiratory Research 2017 18:130

    Published on:

  38. Content type: Research

    Azithromycin, an antibiotic used for multiple infectious disorders, exhibits anti-inflammatory effects, but the molecular basis for this activity is not well characterized. Azithromycin inhibits IL-1β-mediated...

    Authors: Elizabeth A. Lendermon, Tiffany A. Coon, Joseph S. Bednash, Nathaniel M. Weathington, John F. McDyer and Rama K. Mallampalli

    Citation: Respiratory Research 2017 18:131

    Published on:

  39. Content type: Research

    An increasing number of epidemiological and experimental studies have associated exposure to second-hand smoke (SHS) during pregnancy with adverse outcomes in newborns. As we have previously shown in mice, in ute...

    Authors: Alexandra Noël, Rui Xiao, Zakia Perveen, Hasan Zaman, Viviana Le Donne and Arthur Penn

    Citation: Respiratory Research 2017 18:104

    Published on:

  40. Content type: Research

    Tuberculosis (TB) is one of the most common infectious diseases worldwide. During active tuberculosis, T helper (Th) 17 cells are decreased, however the association with inhibitory immune regulation is unclear.

    Authors: Chin-Chung Shu, Ming-Fang Wu, Jann-Yuan Wang, Hsin-Chih Lai, Li-Na Lee, Bor-Luen Chiang and Chong-Jen Yu

    Citation: Respiratory Research 2017 18:128

    Published on:

  41. Content type: Research

    Treatment of severe asthma may include high dose systemic-steroid therapy which is associated with substantial additional morbidity. This study estimates the additional healthcare costs associated with steroid...

    Authors: L. E. Barry, J. Sweeney, C. O’Neill, D. Price and L. G. Heaney

    Citation: Respiratory Research 2017 18:129

    Published on:

  42. Content type: Research

    Pulmonary arterial hypertension (PAH) is a devastating disease that lacks sufficient treatment. Studies have shown that the Nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome contributes ...

    Authors: Jie Yin, Shuling You, Haopeng Liu, Li Chen, Chengdong Zhang, Hesheng Hu, Mei Xue, Wenjuan Cheng, Ye Wang, Xinran Li, Yugen Shi, Nannan Li, Suhua Yan and Xiaolu Li

    Citation: Respiratory Research 2017 18:127

    Published on:

  43. Content type: Research

    β2-adrenoceptor agonists have been shown to reduce the lipopolysaccharide (LPS)-induced cytokine release by human monocyte-derived macrophages (MDMs). We compare the expression of β2-adrenoceptors and the inhibit...

    Authors: Tatiana Victoni, Hélène Salvator, Charlotte Abrial, Marion Brollo, Luis Cristovão Sobrino Porto, Vincent Lagente, Emmanuel Naline, Stanislas Grassin-Delyle and Philippe Devillier

    Citation: Respiratory Research 2017 18:126

    Published on:

  44. Content type: Research

    Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Inflammatory cytokines play a significant role in IPF pathology. However, the fibroblast itself is also believed to be t...

    Authors: Gali Epstein Shochet, Elizabetha Brook, Lilach Israeli-Shani, Evgeny Edelstein and David Shitrit

    Citation: Respiratory Research 2017 18:122

    Published on:

  45. Content type: Research

    Pulmonary function measurements are important when studying respiratory disease models. Both resistance and compliance have been used to assess lung function in mice. Yet, it is not always clear how these para...

    Authors: Fien C. Devos, André Maaske, Annette Robichaud, Lore Pollaris, Sven Seys, Carolina Aznar Lopez, Erik Verbeken, Matthias Tenbusch, Rik Lories, Benoit Nemery, Peter HM Hoet and Jeroen AJ Vanoirbeek

    Citation: Respiratory Research 2017 18:123

    Published on:

  46. Content type: Research

    Beta-blockers are commonly prescribed for patients with cardiovascular disease. Providers have been wary of treating chronic obstructive pulmonary disease (COPD) patients with beta-blockers due to concern for ...

    Authors: Sean Duffy, Robert Marron, Helen Voelker, Richard Albert, John Connett, William Bailey, Richard Casaburi, J. Allen Cooper Jr., Jeffrey L. Curtis, Mark Dransfield, MeiLan K. Han, Barry Make, Nathaniel Marchetti, Fernando Martinez, Stephen Lazarus, Dennis Niewoehner…

    Citation: Respiratory Research 2017 18:124

    Published on:

  47. Content type: Research

    Primitive lung cancers developed on lung fibroses are both diagnostic and therapeutic challenges. Their incidence may increase with new more efficient lung fibrosis treatments. Our aim was to describe a cohort...

    Authors: Alice Guyard, Claire Danel, Nathalie Théou-Anton, Marie-Pierre Debray, Laure Gibault, Pierre Mordant, Yves Castier, Bruno Crestani, Gérard Zalcman, Hélène Blons and Aurélie Cazes

    Citation: Respiratory Research 2017 18:120

    Published on:

2017 Journal Metrics

Advertisement