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  1. Content type: Research

    The incidence of asthma is increasing at an alarming rate. While the current available therapies are effective, there are associated side effects and they fail to adequately control symptoms in all patient sub...

    Authors: Katie Baker, Kristof Raemdonck, Robert J. Snelgrove, Maria G. Belvisi and Mark A. Birrell

    Citation: Respiratory Research 2017 18:55

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  2. Content type: Research

    Ku80 is a DNA repair protein which involves in cell apoptosis and chemoresistance. However, it is unclear whether Ku80 correlates with the efficiency of neoadjuvant chemotherapy in human lung adenocarcinoma, a...

    Authors: Bin Shang, Yang Jia, Gang Chen and Zhou Wang

    Citation: Respiratory Research 2017 18:56

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  3. Content type: Research

    Right ventricular structure and function is a major predictor of outcomes in pulmonary hypertension (PH), yet the underlying mechanisms remain poorly understood. Growing evidence suggests the importance of aut...

    Authors: Yan Deng, Weifeng Wu, Shenglan Guo, Yuming Chen, Chang Liu, Xingcui Gao and Bin Wei

    Citation: Respiratory Research 2017 18:53

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  4. Content type: Research

    Lung cancer (LC) is still the most common cause of cancer related deaths worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of all LC cases but is not a single entity. It is now accepted that, apar...

    Authors: M. Vesel, J. Rapp, D. Feller, E. Kiss, L. Jaromi, M. Meggyes, G. Miskei, B. Duga, G. Smuk, T. Laszlo, I. Karner and J.E. Pongracz

    Citation: Respiratory Research 2017 18:52

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  5. Content type: Research

    Cigarette smoke (CS) is associated with lower numbers of circulating stem cells and might severely affect their mobilization, trafficking and homing. Our study was designed to demonstrate in an animal model of...

    Authors: Olga Tura-Ceide, Borja Lobo, Tanja Paul, Raquel Puig-Pey, Núria Coll-Bonfill, Jéssica García-Lucio, Valérie Smolders, Isabel Blanco, Joan A. Barberà and Víctor I. Peinado

    Citation: Respiratory Research 2017 18:50

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  6. Content type: Research

    Although caffeine and glucocorticoids are frequently used to treat chronic lung disease in preterm neonates, potential interactions are largely unknown. While anti-inflammatory effects of glucocorticoids are w...

    Authors: Markus Fehrholz, Kirsten Glaser, Christian P. Speer, Silvia Seidenspinner, Barbara Ottensmeier and Steffen Kunzmann

    Citation: Respiratory Research 2017 18:51

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  7. Content type: Research

    Agricultural environments are contaminated with organic dusts containing bacterial components. Chronic inhalation of organic dusts is implicated in respiratory diseases. CD14 is a critical receptor for gram-ne...

    Authors: Tricia D. LeVan, Lynette M. Smith, Art J. Heires, Ted R. Mikuls, Jane L. Meza, Lisa A. Weissenburger-Moser and Debra J. Romberger

    Citation: Respiratory Research 2017 18:49

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  8. Content type: Letter to the Editor

    Mast cells are accumulated in advanced chronic obstructive pulmonary disease (COPD), and interleukin (IL)-17 signaling plays a role in disease progression. The expression, localization and functional relevance...

    Authors: Abraham B. Roos, Michiko Mori, Harpreet K. Gura, Axel Lorentz, Leif Bjermer, Hans Jürgen Hoffmann, Jonas S. Erjefält and Martin R. Stampfli

    Citation: Respiratory Research 2017 18:48

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  9. Content type: Letter to the Editor

    Pulmonary arterial hypertension (PAH) is a severe form of pulmonary hypertension that combines multiple alterations of pulmonary arteries, including, in particular, thrombotic and plexiform lesions. Multiple-p...

    Authors: Florence Coste, Christelle Guibert, Julie Magat, Emma Abell, Fanny Vaillant, Mathilde Dubois, Arnaud Courtois, Philippe Diolez, Bruno Quesson, Roger Marthan, Jean-Pierre Savineau, Bernard Muller and Véronique Freund-Michel

    Citation: Respiratory Research 2017 18:47

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  10. Content type: Research

    Airway fibrosis is one of the pathological features of chronic obstructive pulmonary disease (COPD), and recent studies revealed that acetylcholine plays an important role in the development of airway remodeli...

    Authors: Yukiko Namba, Shinsaku Togo, Miniwan Tulafu, Kotaro Kadoya, Kumi Yoneda Nagahama, Hikari Taka, Naoko Kaga, Akira Orimo, Xiangde Liu and Kazuhisa Takahashi

    Citation: Respiratory Research 2017 18:46

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  11. Content type: Research

    Prior studies of clinical prognostication in idiopathic pulmonary fibrosis (IPF) using computed tomography (CT) have often used subjective analyses or have evaluated quantitative measures in isolation. This st...

    Authors: Samuel Y. Ash, Rola Harmouche, Diego Lassala Lopez Vallejo, Julian A. Villalba, Kris Ostridge, River Gunville, Carolyn E. Come, Jorge Onieva Onieva, James C. Ross, Gary M. Hunninghake, Souheil Y. El-Chemaly, Tracy J. Doyle, Pietro Nardelli, Gonzalo V. Sanchez-Ferrero, Hilary J. Goldberg, Ivan O. Rosas…

    Citation: Respiratory Research 2017 18:45

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  12. Content type: Letter to the Editor

    Severe asthma is characterised by a variety of symptoms, which include chronic cough, however the mechanisms responsible for cough reflex hypersensitivity in asthma remain poorly elucidated. Current asthma pat...

    Authors: Sushiladevi Natarajan, Robert C. Free, Peter Bradding, Lorcan McGarvey and Salman Siddiqui

    Citation: Respiratory Research 2017 18:44

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  13. Content type: Research

    Solitary fibrous tumors of the pleura (SFTP) are rare neoplasia of the chest. A subset of SFTP follows a malignant course, sometimes several years after complete resection. Traditional scoring systems based on...

    Authors: Matthias Brock, Selma Hottinger, Matthias Diebold, Alex Soltermann, Wolfram Jochum, Malcolm Kohler, Lars C. Huber and Daniel P. Franzen

    Citation: Respiratory Research 2017 18:43

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  14. Content type: Research

    Growth differentiation factor-15 (GDF-15), a cytokine associated with cardiovascular mortality, increases during chronic obstructive pulmonary disease (COPD) exacerbations, but any role in stable COPD is unkno...

    Authors: Carlos H. Martinez, Christine M. Freeman, Joshua D. Nelson, Susan Murray, Xin Wang, Matthew J. Budoff, Mark T. Dransfield, John E. Hokanson, Ella A. Kazerooni, Gregory L. Kinney, Elizabeth A. Regan, J. Michael Wells, Fernando J. Martinez, MeiLan K. Han and Jeffrey L. Curtis

    Citation: Respiratory Research 2017 18:42

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  15. Content type: Research

    Asthma is characterized by a heterogeneous inflammatory profile and can be subdivided into T(h)2-high and T(h)2-low airway inflammation. Profiling of a broader panel of airway cytokines in large unselected pat...

    Authors: Sven F. Seys, Hans Scheers, Paul Van den Brande, Gudrun Marijsse, Ellen Dilissen, Annelies Van Den Bergh, Pieter C. Goeminne, Peter W Hellings, Jan L. Ceuppens, Lieven J Dupont and Dominique M. A. Bullens

    Citation: Respiratory Research 2017 18:39

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  16. Content type: Research

    It is known that tissue macrophages derive not only from blood monocytes but also from yolk sac or fetal liver, and the tissue of residence guides their function. When isolated, they lose tissue specific signa...

    Authors: Erica Bazzan, Graziella Turato, Mariaenrica Tinè, Claudia M. Radu, Elisabetta Balestro, Chiara Rigobello, Davide Biondini, Marco Schiavon, Francesca Lunardi, Simonetta Baraldo, Federico Rea, Paolo Simioni, Fiorella Calabrese, Marina Saetta and Manuel G. Cosio

    Citation: Respiratory Research 2017 18:40

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  17. Content type: Research

    Myofibroblasts play a major role in the synthesis of extracellular matrix (ECM) and the stimulation of these cells is thought to play an important role in the development of silicosis. The present study was un...

    Authors: Yan Liu, Hong Xu, Yucong Geng, Dingjie Xu, Lijuan Zhang, Yi Yang, Zhongqiu Wei, Bonan Zhang, Shifeng Li, Xuemin Gao, Ruimin Wang, Xianghong Zhang, Darrell Brann and Fang Yang

    Citation: Respiratory Research 2017 18:38

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  18. Content type: Research

    Periostin is a biomarker indicating the presence of type 2 inflammation and submucosal fibrosis; serum periostin levels have been associated with asthma severity. Macrolides have immunomodulatory effects and a...

    Authors: Kosaku Komiya, Shoichiro Ohta, Kazuhiko Arima, Masahiro Ogawa, Shoichi Suzuki, Yasutaka Mitamura, Satoshi Nunomura, Yasuhiro Nanri, Tomohito Yoshihara, Atsushi Kawaguchi, Jun-ichi Kadota, Bruce K. Rubin and Kenji Izuhara

    Citation: Respiratory Research 2017 18:37

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  19. Content type: Research

    Co-exposure to cigarette smoke and alcohol leads to the generation of high concentrations of acetaldehyde and malondialdehyde in the lung. These aldehydes being highly electrophilic in nature react with biolog...

    Authors: Muna Sapkota, Jane M. DeVasure, Kusum K. Kharbanda and Todd A. Wyatt

    Citation: Respiratory Research 2017 18:36

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  20. Content type: Research

    The International Classification of Diseases (ICD) has been grouping the allergic and hypersensitivity disorders involving the respiratory tract under topographic distribution, regardless of the underlying mec...

    Authors: Luciana Kase Tanno, Moises Calderon, Jeffrey F. Linzer Sr, Robert J.G. Chalmers and Pascal Demoly

    Citation: Respiratory Research 2017 18:34

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  21. Content type: Letter to the Editor

    We designed a crossover and placebo-controlled trial to investigate the impact of a 1-h acute vaping session of nicotine-free and flavour-free e-liquid on the pulmonary functions and respiratory mechanics of h...

    Authors: Marie-Ève Boulay, Cyndi Henry, Ynuk Bossé, Louis-Philippe Boulet and Mathieu C. Morissette

    Citation: Respiratory Research 2017 18:33

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  22. Content type: Research

    Recently, the IMPRES study revealed that systemic imatinib improves exercise capacity in patients with advanced pulmonary arterial hypertension. Imatinib blocks the tyrosine kinase activity of the platelet-der...

    Authors: Nina A. Maihöfer, Said Suleiman, Daniela Dreymüller, Paul W. Manley, Rolf Rossaint, Stefan Uhlig, Christian Martin and Annette D. Rieg

    Citation: Respiratory Research 2017 18:32

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    The Erratum to this article has been published in Respiratory Research 2017 18:121

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