Fig. 3

Increased levels of octanoylcarnitine are most closely associated with Class 2 ARDS. Quantile-based g-computation analysis was performed to determine which acylcarnitines were most likely to distinguish between Class 1 and Class 2 ARDS while correcting for age, sex, and creatinine as a measure of renal function. a Acylcarnitines were ranked by weights for Class 2 relative to Class 1 ARDS, (**) indicating P = 0.0014. b Graph shows the probability Pr(Y = 1) of the Class 2 phenotype plotted against joint exposure quantile with 95% confidence interval shown by the gray line. The black solid line shows the marginal structural model (MSM) and smooth conditional fit by the gray solid line