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Fig. 1 | Respiratory Research

Fig. 1

From: Integrated bulk and single-cell RNA-sequencing reveals SPOCK2 as a novel biomarker gene in the development of congenital pulmonary airway malformation

Fig. 1

Identification of DEGs between CPAM and control samples by transcriptome sequencings. (A) Discrimination of CPAM to control by Principal Component Analysis (PCA) in RNA-seq expression profiles. Samples of CPAM and control were colored in blue and orange dots, respectively. (B) Volcano plot representation of DEGs between CPAM and control. Each point in the plot indicated one gene, vertical lines refer to 2-fold change and the horizontal line corresponds to P-value of 0.05. (C) The number of significantly up-regulated and down-regulated genes (FDR < 0.05 and a log2 FC > 1 or log2 FC < -1) were illustrated by yellow and gray bars, respectively. (D) Heatmap of the most DEGs in CPAM and control samples. Top 50 up-regulated or down-regulated genes between CPAM and control were shown

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Respiratory Research

ISSN: 1465-993X

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