Fig. 5
From: Respiratory microbiota and radiomics features in the stable COPD patients
Comparison of alpha diversity and community composition between Aspergillus cluster and Candida cluster. (A) JSD cluster stratification for sputum fungi in 30 COPD patients, cluster 1 was defined as Aspergillus cluster(n = 17), cluster 2 was defined as Candida cluster(n = 13). (B) Comparison of alpha diversity (Chao and Shannon indices) between the two fungal clusters. (C) PCoA analysis based on the Weighted UniFrac distance. (D) Significantly differing fungi between Aspergillus cluster and Candida cluster at the phylum level. (E) Significantly differing fungi between Aspergillus cluster and Candida cluster at the genus level. (F) DLco/VA%pred, smoking duration, and smoking pack year were associated with Chao and Shannon indices of bacteria by linear regression. (G) Some fungi at the genus level were associated with clinical characteristics and pulmonary function based on Spearman correlation. Red indicates positive correlation; blue indicates negative correlation(* 0.01 ≤ FDR P<0.05, ** 0.001 ≤ FDR P<0.01, *** FDR P < 0.001)