Fig. 3
From: Respiratory microbiota and radiomics features in the stable COPD patients
Comparison of alpha diversity and community composition between the Streptococcus cluster and the Rothia cluster. (A) JSD cluster stratification for sputum bacteria in 52 COPD patients, 1 was defined as Streptococcus cluster (n = 33), cluster 2 was defined as Rothia cluster (n = 19). (B) Comparison of alpha diversity (Chao and Shannon indices) between the two bacterial clusters. (C) PCoA analysis based on the Weighted UniFrac distance. (D) Significantly differing bacteria between the Streptococcus cluster and the Rothia cluster at the phylum level. (E) Significantly differing bacteria between the Streptococcus cluster and the Rothia cluster at the genus level. (F) DLco/VA%pred and smoking duration were associated with Chao and Shannon indices of bacteria by linear regression. (G) Some bacteria at the genus level were associated with clinical characteristics and pulmonary function based on Spearman correlation. Red indicates positive correlation; blue indicates negative correlation(* 0.01 ≤ FDR P<0.05, ** 0.001 ≤ FDR P<0.01, *** FDR P < 0.001).