Fig. 3
From: Submersion and hypoxia inhibit alveolar epithelial Na+ transport through ERK/NF-κB signaling pathway
Effect of hypoxia on ENaC and associated signal pathways on A549 and mouse AT2 cells. A, C Representative graph of HIF-1α, α-ENaC, ERK1/2, and NF-κB signaling pathways under hypoxia. B, D The statistical data obtained from Western Blot and quantified through gray analysis. *P < 0.05, **P < 0.01, ***P < 0.001, compared with Control group. Mann-Whitney U test with Bonferroni correction and One-way ANOVA followed by Bonferroni’s test were used to analyze the difference of the means for significance. n = 4–6