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Table 2 Analyses of the relationship between SPSs and recurrence after BAE based on different statistical models

From: Does the presence of systemic artery–pulmonary circulation shunt during bronchial arterial embolization increase the recurrence of noncancer-related hemoptysis? A retrospective cohort study

Model

Parameters

Level

HR (95% CI)

P value

Model 1

SPSs

Present

3.37 (2.07–5.47)

 < 0.001

  

Absent

Reference

 

Model 2

SPSs

Present

1.96 (1.11–3.49)

0.021

  

Absent

Reference

 
 

Age

1.00 (0.98–1.02)

0.739

 

Sex

Female

1.42 (0.79–2.54)

0.244

  

Male

Reference

 
 

Duration of hemoptysis

> 6 months

1.54 (0.92–2.57)

0.098

  

≤ 6 months

Reference

 
 

Underlying lung disease

  

0.823

  

Bronchiectasis

0.91 (0.18–4.56)

0.909

  

Tuberculosis sequela

0.99 (0.19–5.03)

0.989

  

Chronic pneumonia

0.47 (0.06–3.74)

0.478

  

Cryptogenic hemoptysis

Reference

 
 

Volume of hemoptysis

  

0.672

  

 ≥ 300 ml/d

1.11 (0.58–2.12)

0.744

  

100–300 ml/d

1.27 (0.75–2.16)

0.376

  

 < 100 ml/d

Reference

 
 

Smoking

Present

1.03 (0.56–1.89)

0.924

  

Absent

Reference

 
 

Hypertension

Present

0.87 (0.48–1.60)

0.663

  

Absent

Reference

 
 

Disease extent (number of affected lobes)

1.32 (0.99–1.75)

0.058

 

Presence of pleural thickening

Present

1.04 (0.55–1.97)

0.901

  

Absent

Reference

 
 

Lung destruction

Present

1.77 (0.80–3.88)

0.157

  

Absent

Reference

 
 

Number of culprit BAs

0.89 (0.69–1.14)

0.355

 

Presence of culprit NBSAs

Present

1.58 (0.92–2.71)

0.098

  

Absent

Reference

 
 

Embolization materials

  

0.443

  

Gelatin sponge

2.14 (0.66–6.93)

0.206

  

Microsphere

0.97 (0.45–2.09)

0.938

  

PVA

Reference

 

Model 3

SPSs

Present

2.29 (1.34–3.92)

0.002

  

Absent

Reference

 
 

Duration of hemoptysis

 > 6 months

2.00 (1.24–3.23)

0.004

  

 ≤ 6 months

Reference

 
 

Presence of culprit NBSAs

Present

1.79 (1.09–2.92)

0.021

  

Absent

Reference

 

Model 4

SPSs

Present

2.39 (1.44–3.97)

0.001

  

Absent

Reference

 
 

Duration of hemoptysis

 > 6 months

1.78 (1.10–2.88)

0.020

  

 ≤ 6 months

Reference

 
 

Disease extent (number of affected lobes)

1.30 (1.02–1.64)

0.033

 

Lung destruction

Present

2.07 (1.03–4.18)

0.042

  

Absent

Reference

 
  1. BAs bronchial arteries, CI confidence interval, HR hazard ratio, NBSAs nonbronchial systemic arteries, SPSs systemic artery–pulmonary circulation shunts, PVA polyvinyl alcohol