Table 7 Comparison of biomarkers between survivors and non-survivors in the first sample
From: IL-6 and cfDNA monitoring throughout COVID-19 hospitalization are accurate markers of its outcomes
Survivors N = 74 | Non-survivors N = 19 | p | |
|---|---|---|---|
Leukocytes/mm3 | 7200 [5425;8775] | 9800 [6600;13150] | 0.028 |
Neutrophils/mm3 | 5050 [3725;6550] | 8400 [4950;11750] | 0.009 |
Lymphocytes/mm3 | 1200 [800;1600] | 700 [532.50;800] | 0.001 |
N/L ratio | 4.46 [2.51;7.72] | 13.50 [6.75;20.95] | 0.001 |
Platelet/mm3 | 245,000 [168750;279750] | 228,000 [192000;327000] | 0.675 |
CRP (mg/L) | 33.90 [11.70;95.10] | 104.10 [59.20;197.00] | 0.008 |
PCT (ng/mL) | 0.07 [0.04;0.11] | 0.14 [0.08;0.60] | 0.025 |
LDH (U/L) | 255.00 [208.50;366.50] | 323.00 [237.50;403.50] | 0.223 |
D-Dimer (µg/L) | 828.50 [471.75;1378.50] | 1533.50 [1009.75;2671.00] | 0.009 |
Ferritin (ng/mL) | 427.30 [176.00;623.90] | 491.70 [392.35;963.60] | 0.110 |
TNF-α (pg/mL) | 37.84 [31.76;44.02] | 40.91 [32.95;49.72] | 0.194 |
IL-8 (pg/mL) | 42.11 [33.18;56.48] | 61.83 [52.88;89.06] | 0.016 |
IL-1β (pg/mL) | 50.63 [43.09;58.71] | 53.75 [45.44;65.57] | 0.314 |
IFN-ʏ (pg/mL) | 132.22 [119.97;154.89] | 144.93 [117.45;166.73] | 0.737 |
IL-17A (pg/mL) | 15.67 [10.79;22.80] | 19.40 [13.35;22.53] | 0.287 |
P-Selectin (ng/mL) | 49.25 [35.63;71.35] | 53.59 [36.85;69.489] | 0.900 |
G-CSF (pg/mL) | 134.22 [118.12;153.99] | 160.09 [139.92;184.10] | 0.012 |
IL-6 (pg/mL) | 25.91 [5.77;51.55] | 66.91 [38.36;162.70] | 0.001 |
cfDNA (ng/mL) | 6.87 [4.01;10.81] | 14.98 [7.73;22.51] | 0.002 |
SaO2/FiO2 | 452.00 [425.50;462.00] | 380.00 [323.00;416.50] | 0.003 |
SaO2 (%) | 95.00 [90.00;97.00] | 85.00 [75.50;86.50] | < 0.001 |