Fig. 4

Responsiveness to inositol exposure in IPF and ASS1-deficient normal lung fibroblasts. A Representative Western blot images of inositol-responsive molecules and profibrotic markers in IPF lung fibroblasts upon exposure to inositol. B Quantification of protein expression levels from (A) using ImageJ software. Data are expressed as mean ± SE, n = 3. C Representative Western blot images of inositol-responsive molecules and profibrotic markers in control and ASS1-knockdown normal fibroblasts treated with or without inositol. D Quantification of protein expression levels from (C) using ImageJ software. Data are expressed as mean ± SE, n = 3