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Table 3 Typical cancer marker concentrations in peripheral blood of NSCLC (including SCC and AC) patients with or without cancer cell metastasis

From: Correlation analysis of lung mucosa-colonizing bacteria with clinical features reveals metastasis-associated bacterial community structure in non-small cell lung cancer patients

Index

NSCLC

SCC

AC

No met

Met

No met

Met

No met

Met

 

(n = 22)

(n = 31)

(n = 18)

(n = 13)

(n = 4)

(n = 18)

CEA

      

Average

3.95

353.20

4.20

49.81

2.80

572.40

SD

3.92

914.80

4.30

82.16

0.47

1 162.00

Lower 95% CI

2.21

17.68

2.06

0.16

2.05

-5.62

Upper 95% CI

5.68

688.80

6.34

99.46

3.55

1 150.00

Significance

No

*

No

NSE

      

Average

23.10

30.51

24.51

21.43

16.76

37.06

SD

22.12

32.56

24.35

8.86

1.30

41.31

Lower 95% CI

13.29

18.56

12.40

16.07

14.69

16.52

Upper 95% CI

32.91

42.45

36.62

26.79

18.82

57.61

Significance

No

No

No

CYFRA21-1

      

Average

10.15

19.85

11.26

12.61

5.17

25.07

SD

10.31

27.13

11.12

6.53

1.78

34.65

Lower 95% CI

5.58

9.89

5.73

8.66

2.33

7.84

Upper 95% CI

14.72

29.80

16.78

16.55

8.00

8.17

Significance

No

No

No

CA125

      

Average

57.62

733.40

65.87

63.40

20.50

1 217.00

SD

74.03

2209.0

79.82

66.04

4.04

2 831.00

Lower 95% CI

24.80

-76.85

26.18

23.49

14.07

-190.70

Upper 95% CI

90.45

1 544.0

105.60

103.30

26.93

2625

Significance

No

No

No

SCCA

      

Average

1.87

1.48

2.04

2.16

1.10

0.99

SD

1.68

1.47

1.82

1.76

0.12

1.02

Lower 95% CI

1.13

0.94

1.14

1.10

0.92

0.48

Upper 95% CI

2.61

2.02

2.95

3.23

1.28

1.50

Significance

No

No

No

  1. Note: Data are in ng/mL peripheral venous blood, except for CA125 in units/mL. AFP, alpha fetoprotein; CEA, carcinoembryonic antigen; NSE, neuron-specific enolase; CYFRA21-1, cytokeratin-19-fragment; CA125, carbohydrate antigen 125; SCCA, squamous cell carcinoma antigen