Fig. 4

The relationship between H3K4me3-lncRNA score and immune cell activation-related pathway. (A) Correlation analysis between H3K4me3-lncRNA score and immune cell activation-related pathway. (B) Comparison of immune cell activation-related pathway enrichment score between high and low H3K4me3-lncRNA score groups. Enrichment score was calculated by GSVA analysis. (C) (D) (E) Survival analyses showed a significant impact of immune cell activation related molecular subtypes on outcome. (F) (G) (H) Differences in H3K4me3-lncRNA score between high-and low- CD4⁺ T cell, CD8⁺ T cell, and T cell activation via MHC pathway score groups. (I) (J) (K) The proportion of different score groups of indicated molecular subtypes in the two H3K4me3-lncRNA score patterns. (L) Kaplan–Meier curves showing the predictive value of subgroups stratified by H3K4me3-lncRNA score and CD4⁺ T cell activation. (M) Survival analysis for subgroup patients classified by H3K4me3-lncRNA score and CD8⁺ T cell activation. (N) Kaplan-Meier curves showing the predictive value of subgroups stratified by H3K4me3-lncRNA score and T cell activation via MHC pathway. (*p < 0.05; **p < 0.01; ***p < 0.001)