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Fig. 3 | Respiratory Research

Fig. 3

From: Mitochondrial creatine kinase 1 regulates the cell cycle in non-small cell lung cancer via activation of cyclin-dependent kinase 4

Fig. 3

CKMT1 interacts with CDK4 in cells and the lysate. A, B Interaction of CKMT1 with CDK4 was determined using the Co-immunoprecipitation (co-IP) assay. C Interaction of CKMT1 with CDK4 was determined using the GST Pull-down assay. D, E Immunoblot analyses were performed with Flag-tagged truncated CKMT1 mutants (D) and truncated CDK4 mutants (E). F The cell proliferation assays of various deletions of CKMT1 in CKMT1-knockout A549 cells. G The cell viability assays in A549 cells treated with Palbociclib plus Cyclocreatine (Ccr). ***P < 0.001

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Respiratory Research

ISSN: 1465-993X

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