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Table 2 Risk of active tuberculosis according to the parameters in the diabetes severity score

From: Diabetes severity is strongly associated with the risk of active tuberculosis in people with type 2 diabetes: a nationwide cohort study with a 6-year follow-up

  

Events (n)

Incidence rate (per 1000 person-years)

Model 1*

Model 2*

Model 3*

Duration of diabetes

 < 5 years

12, 608

1.05

1 (Ref.)

1 (Ref.)

1 (Ref.)

 ≥ 5 years

8623

1.68

1.59 (1.55, 1.63)

1.28 (1.25, 1.32)

1.25 (1.21, 1.28)

Number of Oral hypoglycemic agents

 < 3

17, 026

1.16

1 (Ref.)

1 (Ref.)

1 (Ref.)

 ≥ 3

4205

1.71

1.47 (1.43, 1.53)

1.34 (1.29, 1.38)

1.28 (1.23, 1.32)

Use of insulin

No

18, 516

1.17

1 (Ref.)

1 (Ref.)

1 (Ref.)

Yes

2715

2.03

1.73 (1.66, 1.80)

1.56 (1.50, 1.63)

1.47 (1.42, 1.54)

Chronic kidney disease

No

17, 704

1.16

1 (Ref.)

1 (Ref.)

1 (Ref.)

 

Yes

3527

1.89

1.63 (1.57, 1.69)

1.24 (1.19, 1.28)

1.30 (1.25, 1.34)

Cardiovascular disease

No

17, 533

1.17

1 (Ref.)

1 (Ref.)

1 (Ref.)

 

Yes

3698

1.72

1.47 (1.42, 1.53)

1.08 (1.04, 1.12)

1.14 (1.10, 1.19)

  1. *Values are presented as hazard ratio (95% confidence intervals) for risk of tuberculosis
  2. “Ref.” refers to the group treated as a reference group in the analysis
  3. Model 1: unadjusted
  4. Model 2: adjusted for age and sex
  5. Model 3: adjusted for age, sex, BMI, income status, alcohol drinking, smoking, regular exercise, fasting glucose, hypertension, and dyslipidemia