Events (n) | Incidence rate (per 1000 person-years) | Model 1* | Model 2* | Model 3* | ||
---|---|---|---|---|---|---|
Duration of diabetes | < 5 years | 12, 608 | 1.05 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
≥ 5 years | 8623 | 1.68 | 1.59 (1.55, 1.63) | 1.28 (1.25, 1.32) | 1.25 (1.21, 1.28) | |
Number of Oral hypoglycemic agents | < 3 | 17, 026 | 1.16 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
≥ 3 | 4205 | 1.71 | 1.47 (1.43, 1.53) | 1.34 (1.29, 1.38) | 1.28 (1.23, 1.32) | |
Use of insulin | No | 18, 516 | 1.17 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
Yes | 2715 | 2.03 | 1.73 (1.66, 1.80) | 1.56 (1.50, 1.63) | 1.47 (1.42, 1.54) | |
Chronic kidney disease | No | 17, 704 | 1.16 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
Yes | 3527 | 1.89 | 1.63 (1.57, 1.69) | 1.24 (1.19, 1.28) | 1.30 (1.25, 1.34) | |
Cardiovascular disease | No | 17, 533 | 1.17 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
Yes | 3698 | 1.72 | 1.47 (1.42, 1.53) | 1.08 (1.04, 1.12) | 1.14 (1.10, 1.19) |