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Fig. 3 | Respiratory Research

Fig. 3

From: Electronic cigarette menthol flavoring is associated with increased inhaled micro and sub-micron particles and worse lung function in combustion cigarette smokers

Fig. 3

Association Menthol Flavoring in Electronic Cigarettes with Lung Function. The mean FEV1 was 9.9% predicted lower (95% CI 0.1, − 19.8% pred; P = 0.053) while the mean FEV1/FVC was 0.06 lower (95% CI 0.002, − 0.11; P = 0.058) in an unadjusted comparison of 25 users of menthol-flavored ECs with 69 users of other flavored ECs in the COPDGene cohort (see Table 3). These associations persisted after adjustment for age, gender, race, pack years of smoking, as well as the use of nicotine or cannabis-containing vaping products in multivariate models. Specifically, menthol users had on average 9.6% predicted lower FEV1 (95% CI − 0.2, − 19.1% pred; P = 0.04) and 0.06 lower FEV1/FVC (95% CI − 0.01, − 0.12; P = 0.01) compared to users of other flavored products adjusted for these covariates. FEV1 Forced Expiratory Volume in the First Second, FVC Forced Vital Capacity, COPDGene Chronic Obstructive Lung Disease Gene study

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