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Fig. 2 | Respiratory Research

Fig. 2

From: Electronic cigarette menthol flavoring is associated with increased inhaled micro and sub-micron particles and worse lung function in combustion cigarette smokers

Fig. 2

Impact of Menthol Flavoring in Commercially Available Electronic Cigarettes on Inhaled Particle Quantity. Inhaled particle count analysis was performed as in Fig. 1 using HUMITIPAA on popular and off-the-shelf products Vuse Alto Menthol (1.8% nicotine strength) and Vuse Alto Golden Tobacco (1.8% Nicotine) pods, with latter serving as control flavoring. These e-liquids were analyzed by GC–MS (see Table 2) and were found to have PG:VG ratios of 38:52 (Menthol) and 41:53 (Golden Tobacco); hence, we studied particle quantities for all size fractions compared with these PG and VG values in addition to reference 50%. Mann–Whitney U tests was applied for statistical significance analysis between the 50:50 PG:VG, 38% PG and 52% VG solutions against the Vuse Alto Menthol, the 50:50 PG:VG, 41% PG and 53% VG solutions against the Vuse Alto Golden Tobacco, and the Vuse Alto Menthol vs. Vuse Alto Golden Tobacco. *P < 0.05, **P < 0.01. Note significantly higher inhaled particles in menthol- vs. non-menthol-flavored EC (4 independent trials, 5 puffs per trial, each data point representing real-time reading by HUMITIPAA sensor at about every second). Electronic Cigarette; GC–MS gas chromatography–mass spectroscopy, Tob tobacco

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Respiratory Research

ISSN: 1465-993X

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