Fig. 11

CENPO participates in the regulation of cell cycle of LUAD. A The correlation between CENPO expression and CDK1, CDK2, CDK4, CDK6, CCNA, CCNB, CCNC, and CCNE, in the GEPIA2.0 database. B Effects of down-regulation of CENPO expression on cell apoptosis of A549 and HCI-H1299 cells. C Flow cytometry with PI staining was used to detect the effect of CENPO knockdown on the cell cycle distribution of A549 and HCI-H1299 cells. The presented results were representative of experiments repeated at least three times. Data was presented as the mean ± SD (n = 3). *P < 0.05, **P < 0.01 and ***P < 0.001