Table 1 Hospitalizations characteristics for ILD patients with GERD vs. without GERD

Age, mean ± SD

71.20 (15.26)

69.53 (17.19)

 < 0.001

Age group (20–39), n (%)

67,245 (4)

477,374 (7)

 < 0.001

Age group (40–59), n (%)

314,002 (18)

1,313,106 (19)

 < 0.001

Age group (60–79), n (%)

743,468 (42)

2,620,494 (38)

 < 0.001

Age group (80 or more), n (%)

625,867 (36)

2,405,310 (35)

 < 0.001

Female, n (%)

841,440 (48)

2,826,688 (41)

 < 0.001

Race

 < 0.001

White, n (%)

1,298,312 (79)

4,558,471 (72)

Black, n (%)

180,894 (11)

854,095 (14)

Hispanic, n (%)

92,266 (6)

486,648 (8)

Asian or Pacific Islander, n (%)

30,194 (2)

188,144 (3)

Native American, n (%)

8218 (1)

37,738 (1)

Other, n (%)

32,789 (2)

172,435 (3)

Smoking Status

Ever smoker, n (%)

529,037 (30)

1,698,764 (25)

 < 0.001

Interstitial lung disease subtype:

 < 0.001

Idiopathic pulmonary fibrosis, n (%)

63,756 (4)

126,550 (2)

Connective tissue disease-ILD, n (%)

102,620 (6)

211,558 (3)

Hypersensitivity pneumonitis, n (%)

1,506,754 (86)

6,258,846 (92)

Pulmonary sarcoidosis, n (%)

66,706 (4)

198,014 (3)

Unspecified-ILD, n (%)

11,354 (1)

22,574 (0)

Co-morbidities

Respiratory failure, n (%)

749,755 (43)

3,294,179 (48)

 < 0.001

Dependence on long-term Oxygen, n (%)

161,134 (9)

353,694 (5)

 < 0.001

Chronic obstructive lung disease, n (%)

211,515 (12)

655,650 (10)

 < 0.001

Asthma, n (%)

166,251 (9)

364,574 (5)

 < 0.001

Pneumonia, n (%)

265,203 (15)

1,105,779 (16)

 < 0.001

Acute pulmonary embolism, n (%)

27,664 (2)

131,831 (2)

 < 0.001

Pulmonary hypertension, n (%)

117,274 (7)

351,289 (5)

 < 0.001

Obstructive sleep apnea, n (%)

171,273 (10)

377,630 (6)

 < 0.001

Obesity, n (%)

202,655 (12)

612,569 (9)

 < 0.001

Barrett's esophagus, n (%)

16,141 (1)

16,454 (0)

 < 0.001

Hiatal hernia, n (%)

149,978 (9)

164,970 (2)

 < 0.001

Low body mass index, n (%)

78,590 (4)

316,053 (5)

 < 0.001

Frailty, n (%)

5519 (0.3)

16,374 (0.2)

 < 0.001

Elixhauser sum of conditions

Mean ± SD

2.31 (2.54)

2.46 (2.43)

 < 0.001

Median (IQR)

2(4)

2(4)

Hospitalization Characteristics

Length of hospital stay, mean ± SD

8.21 (8.83)

10.40 (12.88)

 < 0.001

In-patient pulmonary Procedures

Bronchoscopy, n (%)

99,748 (6)

463,546 (7)

 < 0.001

Invasive mechanical ventilation, n (%)

265,899 (15)

1,789,034 (26)

 < 0.001

Non-invasive mechanical ventilation, n (%)

95,902 (5)

328,873 (5)

 < 0.001

Mechanical ventilation (invasive and non-invasive), n (%)

26,682 (1.5)

143,626 (2.1)

 < 0.001

Bed size of hospital

 < 0.001

Small, n (%)

307,263 (18)

1,124,413 (17)

Medium, n (%)

483,774 (28)

1,847,496 (27)

Large, n (%)

955,684 (55)

3,824,916 (56)

Region of hospital

 < 0.001

Northeast, n (%)

326,379 (19)

1,373,817 (20)

Midwest, n (%)

427,360 (24)

1,419,100 (21)

South, n (%)

681,228 (39)

2,553,635 (37)

West, n (%)

316,224 (18)

1,470,988 (22)

Academic hospitals, n (%)

974,157 (56)

3,730,909 (55)

 < 0.001

Urban hospitals, n (%)

1,540,479 (88)

6,098,589 (90)

 < 0.001