Variable | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
Factors | OR | 95%CI | P -value | OR | 95%CI | P -value |
Age (years) | 1.013 | 0.991–1.036 | 0.245 |  |  |  |
Sex (Male versus Female) | 0.890 | 0.502–1.607 | 0.717 |  |  |  |
BMI (kg/m2) | 0.958 | 0.895–1.025 | 0.216 |  |  |  |
Smoking state | Â | Â | Â | Â | Â | Â |
Current smoker | Reference | Â | ||||
Ex-smoker | 1.386 | 0.774–2.477 | 0.271 |  |  |  |
Non-smoker | 0.995 | 0.582–1.703 | 0.986 |  |  |  |
Biofuel exposure, (Yes versus No) | 1.364 | 1.126–1.579 | 0.000 | 1.102 | 1.009–1.214 | 0.036 |
Occupational exposure (Yes versus No) | 1.055 | 0.717–1.522) | 0.786 |  |  |  |
CAT score | 1.179 | 1.136–1.225 | <0.001 | 1.372 | 1.274–1.477 | <0.001 |
mMRC (Median, IQR) | Â | Â | Â | Â | Â | Â |
0–1 | Reference | |||||
2–4 | 1.021 | 1.002–1.075 | 0.008 |  |  |  |
CCQ score | 1.077 | 1.049–1.106 | <0.001 |  |  |  |
GOLD group | Â | Â | Â | Â | Â | Â |
 A | Reference |  | ||||
 B | 2.413 | 1.616–2.907 | 0.000 |  |  |  |
 C | 1.043 | 0.583–1.965 | 0.934 |  |  |  |
 D | 1.921 | 1.423–2.214 | 0.001 |  |  |  |
Exacerbations in the past year, (Yes versus No) | 1.321 | 0.914–1.908 | 0.139 |  |  |  |
Treatment | Â | Â | Â | Â | Â | Â |
 LAMA | Reference |  | ||||
 LABA + ICS | 1.011 | 0.521–1.961 | 0.975 |  |  |  |
 LABA + LAMA | 1.988 | 1.216–3.496 | 0.011 |  |  |  |
 LABA + LAMA + ICS | 1.894 | 1.148–3.125 | 0.012 |  |  |  |
PSQI ≤ 5 | 2.364 | 1.388–3.268 | 0.001 | 3.112 | 1.873–4.711 | <0.001 |
Risk of OSAS | 1.002 | 0.789–1.314 | 0.852 |  |  |  |
Anxiety | 0.957 | 0.568–1.127 | 0.431 |  |  |  |
Depresion | 1.018 | 0.498–1.637 | 0.612 |  |  |  |