Table 1 Highest and lowest 15 significantly changed proteins in the fibrotic honeycomb airway cells compared to fibrotic uninvolved airway cells
From: Morphologically intact airways in lung fibrosis have an abnormal proteome
Increased in fibrotic honeycomb airway cells | Decreased in fibrotic honeycomb airway cells | ||||
|---|---|---|---|---|---|
Protein | Log2 | FDR | Protein | Log2 | FDR |
BPIFB1 | 3.97 | 4.60E−24 | CEP135 | − 1.30 | 3.18E−02 |
DHRS9 | 3.79 | 1.40E−03 | COL8A1 | − 1.23 | 3.28E−03 |
MUC5B | 3.65 | 1.70E−21 | FBLN2 | − 1.00 | 2.16E−02 |
S100P | 2.77 | 2.40E−19 | LRRC45 | − 0.90 | 2.88E−02 |
FAM3D | 2.73 | 2.90E−02 | TTC21B | − 0.86 | 3.29E−03 |
BPIFA1 | 2.52 | 7.40E−04 | LAMB2 | − 0.75 | 3.40E−04 |
LCN2 | 2.20 | 3.13E−13 | APCS | − 0.74 | 4.45E−02 |
CRABP2 | 2.08 | 3.22E−02 | CGN | − 0.74 | 1.45E−02 |
DMBT1 | 1.74 | 4.82E−03 | FBN1 | − 0.72 | 2.24E−02 |
CPD | 1.68 | 2.30E−06 | IFT57 | − 0.72 | 4.30E−05 |
ST6GAL1 | 1.64 | 1.02E−02 | NCEH1 | − 0.69 | 6.30E−04 |
IGJ | 1.55 | 3.763E−03 | PLG | − 0.63 | 8.00E−03 |
AGR2 | 1.53 | 1.00E−05 | H1F0 | − 0.62 | 6.25E−03 |
FKBP11 | 1.49 | 1.53E−02 | CYP51A1 | − 0.60 | 2.90E−02 |
SLPI | 1.46 | 1.80E−04 | CERS2 | − 0.59 | 2.59E−02 |