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Fig. 2 | Respiratory Research

Fig. 2

From: Morphologically intact airways in lung fibrosis have an abnormal proteome

Fig. 2

Spatial proteomic analysis of the fibrotic airway cells. Fibrotic and non-fibrotic control specimens were subjected to laser capture microdissection coupled mass spectrometry (LCM-MS) to collect non-fibrotic airway cells (n = 6 control patients), fibrotic uninvolved airway cells (n = 10 UIP patients), and fibrotic honeycomb airway cells (n = 10 UIP patients). A Venn diagram showing the number of proteins found in each airway cell type. B 3-D Principal component analysis showing that the non-fibrotic airway cells (red dots) cluster away from the fibrotic airway cells (the other dots). Surprisingly, fibrotic uninvolved airway cells (yellow dots) and honeycomb airway cells (green dots) cluster together

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