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Table 1 Comparison of patient characteristics

From: Pseudomonas aeruginosa isolation is an important predictor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a multicenter cohort study

Category

All patients (N = 588)

Recurrent hemoptysis

Recurrent severe hemoptysis

No (N = 321)

Yes (N = 267)

p value

No (N = 474)

Yes (N = 114)

p value

Age, years

59.9 ± 12.6

59.8 ± 12.5

59.9 ± 12.7

0.899

59.2 ± 12.7

62.4 ± 11.9

0.016

Sex (female)

276 (46.9)

157 (48.9)

119 (44.6)

0.294

218 (46.0)

58 (50.9)

0.348

Body mass index, kg m−2

21.6 ± 2.8

21.4 ± 3.4

21.4 ± 3.4

0.608

21.6 ± 3.1

21.3 ± 3.1

0.405

Smoking

 Non-smoker

392 (66.7)

203 (62.9)

189 (71.2)

0.071

320 (66.9)

72 (65.5)

0.345

 Ex-smoker

143 (24.3)

84 (26.2)

59 (22.1)

112 (23.4)

31 (28.2)

 Current smoker

53 (9.0)

35 (10.9)

18 (6.7)

46 (9.6)

7 (6.4)

Duration of bronchiectasis, years

10 (5.20)

10 (4.20)

20 (8.30)

< 0.001

10 (5.20)

20 (10.30)

< 0.001

Symptoms

Duration of hemoptysis, years

7 (2.20)

5 (1.12)

10 (2.20)

0.001

5 (1.20)

10 (3.30)

0.001

Hemoptysis volume, mL

180 (150.210)

180 (150.200)

200 (150.220)

0.078

180 (140.203)

200 (158.235)

0.013

24-h sputum volume†

 Minimal

139 (23.6)

97 (30.2)

42 (15.7)

< 0.001

123 (25.9)

16 (14.0)

0.005

 Few

225 (38.3)

126 (39.3)

99 (37.1)

182 (38.4)

43 (37.7)

 Medium

159 (27.0)

77 (24.0)

82 (30.7)

125 (26.4)

34 (29.8)

 Massive

65 (11.1)

21 (6.5)

44 (16.5)

44 (9.3)

21 (18.4)

Hemoptysis related factors

 Hypertension

130 (22.1)

69 (21.5)

61 (22.8)

0.694

106 (22.4)

24 (21.1)

0.762

 Thrombocytopenia

19 (3.2)

10 (3.1)

9 (3.4)

0.862

15 (3.2)

4 (3.5)

0.773

 Anticoagulant

22 (3.7)

8 (2.5)

14 (5.2)

0.080

17 (3.6)

5 (4.4)

0.783

Pathogen findings

 Isolation of Pseudomonas aeruginosa

140 (23.8)

44 (13.7)

96 (36.1)

< 0.001

84 (17.7)

56 (49.1)

< 0.001

 Isolation of other pathogenic microorganisms*

23 (3.9)

10 (3.1)

13 (4.9)

0.275

21 (4.4)

2 (1.8)

0.281

Radiographic findings

 Number of bronchiectatic lobes ≥ 3

427 (72.6)

196 (61.1)

231 (86.5)

< 0.001

329 (69.4)

98 (86.0)

< 0.001

Bronchoarterial ratio§

 1–2 times

261 (44.4)

176 (54.8)

85 (31.8)

< 0.001

232 (48.9)

29 (25.4)

< 0.001

 2–3times

110 (18.7)

62 (19.3)

48 (18.0)

87 (18.4)

23 (20.2)

 > 3times

217 (36.9)

83 (25.9)

134 (50.2)

155 (32.7)

62 (54.4)

Bronchiectatic type

 Cylindrical

161 (27.4)

113 (35.1)

48 (18.0)

< 0.001

142 (30.0)

19 (16.7)

0.001

 Cystic

91 (15.5)

59 (18.3)

32 (12.0)

79 (16.7)

12 (10.5)

 Mixed

336 (57.1)

149 (46.4)

187 (70.0)

253 (53.4)

83 (72.8)

Emphysema

115 (19.6)

75 (23.4)

40 (15.0)

0.011

96 (20.3)

19 (16.7)

0.386

Atelectasis

161 (27.4)

79 (24.6)

82 (30.7)

0.099

118 (24.9)

43 (37.7)

0.006

Complications after BAE

 Chest tightness

36 (6.1)

19 (5.9)

17 (6.4)

0.188

26 (5.5)

10 (8.8)

0.753

 Chest pain

33 (5.6)

17 (5.3)

16 (6.0)

26 (5.5)

7 (6.1)

 Hematoma at the puncture site

11 (1.9)

5 (1.6)

6 (2.2)

9 (1.9)

2 (1.8)

 Fever

7 (1.2)

6 (1.9)

1 (0.4)

6 (1.3)

1 (0.9)

 Dysphagia

5 (0.9)

5 (1.6)

0 (0)

5 (1.1)

0 (0)

  1. Data are n (%), mean ± SD, or median (IQR). BAE bronchial artery embolization
  2. †Minimal, few, medium, and massive represented sputum volumes of < 10 mL, 10–50 mL, 50–100 mL, and ≥ 100 mL, respectively
  3. *Other pathogenic microorganisms including Klebsiella pneumoniae, Haemophilus, Acinetobacter baumannii, and Stenotrophomonas maltophilia
  4. §The ratio of bronchia lumen to vessel diameter