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Table 5 Taste-related adverse events (additional “cumulative” analysis)

From: The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial

Filapixant (N = 23)

Placebo (N = 23)

20 mg

80 mg

150 mg

250 mg

(20 mg)

(80 mg)

(150 mg)

(250 mg)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

1 (4.3%)

3 (13.0%)

10 (43.5%)

13 (56.5%)

2 (8.7%)

2 (8.7%)

4 (17.4%)

3 (13.0%)

  1. The table provides the number of patients reporting taste-related adverse events for each dose step where such an event was present, irrespective of the time of its onset. The number of patients reporting taste-related AEs might decrease from one dose step to the next when taste disorders disappear in a patient. Taste-related adverse events were ageusia, dysgeusia, hypogeusia, and taste disorder without further specification (MedDRA v22.0 preferred terms)