Table 1 Patient baseline characteristics
Age [years] (mean ± SD; range) | 60.4 ± 9.1; 43–77 |
Age classification (< 65 years: ≥ 65 years) (N) | 14 (16%): 9 (39%) |
Sex (male: female ratio) (N) | 5 (22%): 18 (78%) |
Body weight [kg] (mean ± SD; range) | 72.5 ± 11.9; 49.3–95.4 |
Body mass index [kg/m2] (mean ± SD; range) | 26.8 ± 4.21; 19.6–34.3 |
Race | |
Black or African American (N) | 1 (4.3%) |
White (N) | 22 (95.7%) |
Ethnicity | |
Not Hispanic or Latino (N) | 23 (100%) |
Smoking history | |
Never (N) | 14 (60.9%) |
Former (N) | 9 (39.1%) |
Other tobacco/cigar/pipe | |
Former (N) | 2 (8.7%) |
Never (N) | 21 (91.35) |
Alcohol use | |
Abstinent (N) | 5 (21.75) |
Light (N) | 16 (69.65) |
Moderate (N) | 2 (8.75) |
Duration of cough [years]a (mean ± SD; range) | 12.2 ± 10.02; 2–45 |
Baseline cough count (Period 1) | |
24-h cough count [coughs/h] (geometric mean ± SD; range) | 28.0 / 156; 0.7–513 |
Awake cough count [coughs/h] (geometric mean ± SD; range) | 37.8 / 167; 1.0–745 |
Baseline LCQ scores (Period 1) | |
LCQ total score (mean ± SD; range) | 10.5 ± 3.16; 6.04–15.6 |
LCQ physical domain score (mean ± SD; range) | 3.68 ± 1.10; 1.75–5.38 |
LCQ psychological domain score (mean ± SD; range) | 3.67 ± 1.20; 1.43—5.43 |
LCQ social domain score (mean ± SD; range) | 3.16 ± 1.24; 1.00—5.25 |