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Fig. 5 | Respiratory Research

Fig. 5

From: Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction

Fig. 5

Involvement of FASN in regulating the p38 MAPK/NLRP3/VE-cadherin signaling in MLECs under metabolic stress when subjected to LPS. Representative western blots of p-p38 MAPK (a, g), p38 MAPK (a, g), NLRP3 (c, i), and VE-cadherin (e, k), and corresponding quantitative analysis of p-p38 MAPK/p38 MAPK (b, h), NLRP3 (d, j), and VE-cadherin (f, l) in each group of MLECs. n = 3 biologically independent experiments. One-way ANOVA and LSD or Games–Howell posthoc analysis. Data were represented as mean ± SD

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