Skip to main content
Fig. 1 | Respiratory Research

Fig. 1

From: Benchmarking omics-based prediction of asthma development in children

Fig. 1

Workflow of the asthma development prediction. We collected six types of omics data taken at/before year 1 in the VDAART cohort: (1) GWAS: genome-wide SNP genotyping data and genome-wide association study analysis results; (2) Child miRNA (cord blood); (3) Child mRNA transcriptomics (cord blood); (4) Child microbiome 3–6 months; (5) Child metabolomics at 1 year; (6) Child DNA methylation data (cord blood). We split the subjects into two parts for hold-out validation and cross-validation, respectively. Then, we applied different classifiers to predict the asthma status at year 3 using the omics data. Each method was evaluated using Accuracy, F1 score, AUROC and AUPRC

Back to article page