Skip to main content
Fig. 3 | Respiratory Research

Fig. 3

From: A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancer

Fig. 3

BIRC5 (survivin) acts on cytoplasm and nucleus and is involved in different cellular functions: cell survival, cell cycle progression, and apoptosis. Survivin decreases apoptosis by suppressing caspase-3, 7, and 9. Also, survivin expression is regulated by WNT/β-catenin Signaling and p53 protein; p53 represses survivin expression and the Wnt signaling pathway upregulates survivin

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us