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Fig. 5 | Respiratory Research

Fig. 5

From: Decreased ubiquitin modifying enzyme A20 associated with hyper-responsiveness to ovalbumin challenge following intrauterine growth restriction

Fig. 5

m6A modifications of lung tissues. A The diagram showed RNA methylation levels of four motifs. Noted that the motif of GGACA had the highest abundance. B The heatmap for the specific mRNA sites of m6A modifications in lung tissues between IUGR d1 and control d1 groups. C The relative m6A modification levels of ten specific sites of A20 mRNA in IUGR rats. D The relative m6A modification levels of ten specific sites of endothelin-1 mRNA in IUGR rats. E The bar graph shows that m6A modifications of A20 mRNA in newborn IUGR rats was significantly higher that control group, and persisted into 10 weeks after birth, even during OVA challenge. F The bar graph shows that m6A modifications of endothelin-1 mRNA in newborn IUGR rats was significantly lower that control group, and persisted into 10 weeks after birth, even during OVA challenge. *P < 0.05, **P < 0.01

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Respiratory Research

ISSN: 1465-993X

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