Fig. 2

Identification of ubiquitinated proteins in lung tissues. A 314 ubiquinated sites, 273 ubiquinated peptides, and 187 ubiquinated proteins were identified in lung tissues. B The Veen diagram showed the overlap of identified ubiquitinated proteins between IUGR and control group. C The ubiquitination motifs and conservation of ubiquitination sites. The central K stands for the ubiquitinated protein. The size of each letter is related to the frequency of amino acid residues occurring at that position. D Volcano plot using two factors showing the difference in ubiquitinated peptides between the two groups of samples. The red dots represent significantly differentially expressed ubiquitinated peptides (fold change is greater than 2 and P value is less than 0.05). E Heatmap for differentially expressed ubiquitinated proteins between IUGR and control groups via label-free relative quantitative proteomics