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Fig. 2 | Respiratory Research

Fig. 2

From: Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosis

Fig. 2

Monocyte and macrophage subtype changes in IPF patient lungs. A Macrophage gating protocol and dot plots showing lung AM and MoM distribution in vivo according to CD11c versus CD11b marker expression. B Changes in total macrophages and their subtypes in lungs of patients with IPF. C Gating protocol of monocytes and their subtypes. D Changes in monocyte subtype in lungs of patients with IPF. n = 5 for each group, *indicates P < 0.05, **indicates P < 0.01. All results are representative of at least three independent experiments. IPF idiopathic pulmonary fibrosis, AM alveolar macrophages, MoM monocyte-derived macrophage

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