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Fig. 5 | Respiratory Research

Fig. 5

From: Proteomics and metabolomics profiling reveal panels of circulating diagnostic biomarkers and molecular subtypes in stable COPD

Fig. 5

Integrated analyses of proteomics and metabolomics data. A KEGG enrichment analysis of differentiated expressed proteins (DEPs) and differentiated expressed metabolites (DEMs). B The number of DEPs and DEMs. C Number of proteins and metabolites common involved in one pathway. D Validation study of the final predicted model on mild-to-moderate COPD patients. E PCA analysis of proteomics or (and) metabolomics data. F Heatmap analyses of DEPs and DEMs identified relatively strong or weak proteins-metabolites correlations. G The network analysis between DEPs and DEMs. H Establishment of predictive panels for COPD (single and combined biomarkers analysis)

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