Fig. 7
From: BRD4 is involved in viral exacerbation of chronic obstructive pulmonary disease
IL-6 and IL-8 are significantly induced by CSE and virus and are suppressed by knockdown of BRD4 in bronchial epithelial cells. BEAS-2B cells were treated with CSE and/or infected with influenza virus after transfection with BRD4 siRNA. The relative mRNA levels (fold change) of BRD4 (A), IL-6 (B), and IL-8 (C) in BEAS-2B cells are shown. The protein levels of IL-6 (D) and IL-8 (E) in cell culture supernatant are shown. The data are representative of at least three independent experiments. **P < 0.01