Fig. 4
From: Vascular and pulmonary effects of ibuprofen on neonatal lung development
Representative lung sections stained for von Willebrand Factor (vWF; A–D) or CD31 (E–H) of rat pups kept in room air (RA; open symbols; A, B, E and F) or 100% O2 (solid symbols; C, D, G and H). Pups were injected daily with arginine buffer (circles; A, C, E and G) or ibuprofen (50 mg/kg/day; triangles; B, D, F and H) until 10 days of age. Arrows indicate blood vessels. The number of pulmonary vessels stained with vWF (I) or CD31 (J) was determined on paraffin sections in rat pups on day 10. Values are expressed as mean ± SEM (N = 6–7). ***p < 0.001 versus RA controls