From: Exhaled biomarkers in adults with non-productive cough
Subjects without chronic non-productive cough (n = 55) | Subjects with chronic non-productive cough (n = 14) | p-value | |
---|---|---|---|
Age (years) | 59 (53–67) | 61 (53–67) | 0.654 |
Sex (F/M) | 30/25 | 8/6 | 0.862 |
BMI (kg/m2) | 25.5 (23.7—27.6) | 26.4 (24.9–28.7) | 0.251 |
Former smokers, N (%) | 36 (65%) | 11 (78%) | 0.347 |
Pack-years | 15 (0–26) | (18 (3–40) | 0.342 |
Asthma diagnosis, N (%) | 2 (4%) | 1 (7%) | 0.566 |
hsCRP (mg/L) | 0.91 (0.61–1.40) | 1.75 (0.52–3.70) | 0.180 |
Eosinophils (109 cells/L) | 0.10 (0.10–0.20) | (0.10 (0.08–0.20) | 0.505 |
FeNO (ppb) | 17 (13–28) | 15 (12–21) | 0.396 |
FVC % preda | 95.9 (89.0–100.3) | 104.1 (91.2–109.1) | 0.054 |
FEV1% preda | 93.4 (85.2–97.2) | 97.0 (85.9–105.7) | 0.495 |
FEV1/FVCa | 76.4 (71.2–79.8) | 75.9 (66.1–78.1) | 0.249 |
R5 Hz (kPa/(L/s))a | 0.330 (0.270–0.390) | 0.305 (0.285–0.398) | 0.987 |
R5 Hz % preda | 94.0 (83.9–107.3) | 93.8 (84.6–105.9) | 0.867 |
R5-R20 (kPa/(L/s))a | 0.043 (0.025–0.063) | 0.022 (0.015–0.072) | 0.472 |
R5-R20% preda | 75.8 (45.2–128.8) | 42.5 (29.7–129.0) | 0.453 |
AX (kPa/L)a | 0.213 (0.105–0.328) | 0.143 (0.092–0.401) | 0.710 |
AX % preda | 83.6 (46.6–145.1) | 65.1 (44.8–165.7) | 0.685 |