Table 1 Sociodemographic, anthropometric, and clinical characteristics of individuals with chronic obstructive pulmonary disease at beginning of the study (n = 76)
From: Responsiveness to pulmonary rehabilitation in COPD is associated with changes in microbiota
Characteristics | Intervention group (n = 38) | Control group (n = 38) | p-value |
|---|---|---|---|
Age (years), mean ± SD | 72 ± 9 | 70 ± 7.60 | 0.19a |
Gender, n (%) | 0.57b | ||
Male | 29 (76%) | 31 (82%) | |
Female | 9 (24%) | 7 (18%) | |
BMI (kg/m2), mean ± SD | 26 ± 4 | 26.4 ± 4.8 | 0.72c |
FEV1PP, mean ± SD | 49.2 ± 16.0 | 52.3 ± 19.8 | 0.53a |
FVCPP, mean ± SD | 77.8 ± 17.3 | 76.9 ± 27.9 | 0.68a |
Pack-years, mean ± SD | 42.4 ± 43.0 | 53.0 ± 51.2 | 0.27a |
Comorbidities (CCI), mean ± SD | 4.2 ± 1.4 | 3.8 ± 1.3 | 0.10a |
GOLD grade, n (%) | 0.22d | ||
1 | 3 (8%) | 6 (16%) | |
2 | 14 (37%) | 12 (32%) | |
3 | 20 (53%) | 15 (39%) | |
4 | 1 (3%) | 5 (13%) | |
GOLD group, n (%) | 0.069d | ||
A | 8 (21%) | 17 (45%) | |
B | 20 (53%) | 12 (32%) | |
C | 0 (0%) | 1 (3%) | |
D | 10 (26%) | 8 (21%) | |
Medication, n (%) | |||
ICS | 21 (55%) | 19 (50%) | 0.8d |
LABA | 33 (87%) | 30 (79%) | 0.36d |
LAMA | 24 (63%) | 25 (66%) | > 0.99 |
LTRA | 2 (5%) | 2 (5%) | > 0.99d |
SABA | 9 (24%) | 5 (13%) | 0.37d |
SAMA | 2 (5%) | 0 (5%) | 0.49d |
Macrolides in stability | 0 (0%) | 0 (0%) | > 0.99 |
Number of exacerbations in the last year, n (%) | 0.60b | ||
0 or 1 | 27 (71%) | 29 (76%) | |
≥ 2 or 1 with a hospitalisation | 11 (29%) | 9 (24%) | |
Number of hospitalisations in the last year due to COPD, n (%) | 0.67d | ||
0 | 32 (84%) | 34 (89%) | |
1 | 2 (5%) | 3 (8%) | |
2 | 3 (8%) | 1 (3%) | |
Missing values | 1 (3%) | 0 (0%) | |
mBORG, mean ± SD | 0.8 ± 1.3 | 0.5 ± 1.0 | 0.3a |
CAT, mean ± SD | 17.1 ± 8.1 | 11.7 ± 7.4 | 0.003a |
Walked distance in 6MWT, mean ± SD | 389.0 ± 133.9 | 457.5 ± 82.8 | 0.045a |