Table 1 Characteristics of study populations
| Â | COPDGene | GenKOLS | ECLIPSE | ||||||
|---|---|---|---|---|---|---|---|---|---|
All Subjects | Males | Females | All Subjects | Males | Females | All Subjects | Males | Females | |
Subjects with spirometry | 6631 | 3474 (52.39%) | 3157 (47.61%) | 1658 | 917 (55.31%) | 741 (44.69%) | 1904 | 1258 (66.07%) | 646 (33.93%) |
Mean age, years (SD) | 62.03 (8.84) | 62.38 (8.81) | 61.65 (8.85) | 60.69 (11.05) | 61.88 (11.15) | 59.21 (10.74) | 63.14 (7.51) | 63.62 (7.43) | 62.22 (7.59) |
Mean pack Year History (SD) | 47.27 (26.03) | 51.54 (28.06) | 42.57 (22.68) | 25.98 (17.41) | 29.49 (18.86) | 21.64 (14.28) | 48.7 (27.75) | 52.12 (29.66) | 42.14 (22.20) |
Current smoking (%) | 2594 (39.12%) | 1385 (39.87%) | 1209 (38.30%) | 731 (44.09%) | 377 (41.11%) | 354 (47.77%) | 661 (35.46%)* | 422 (34.20%)* | 239 (37.94%)* |
GOLD II-IV COPD (%) | 2803 (42.27%) | 1564 (45.02%) | 1239 (39.25%) | 853 (51.45%) | 513 (55.94%) | 340 (45.88%) | 1726 (91.08%) | 1155 (92.33%) | 571 (88.66%) |
FEV1, % predicted (SD) | 73.56 (25.90) | 72.41 (26.49) | 74.83 (25.18) | 72.18 (26.17) | 70.06 (26.19) | 74.80 (25.92) | 53.13 (23.23) | 51.33 (22.74) | 56.64 (23.78) |
FEV1, L (SD) | 2.22 (0.95) | 2.51 (1.03) | 1.88 (0.72) | 2.38 (1.10) | 2.66 (1.19) | 2.04 (0.87) | 1.51 (0.78) | 1.63 (0.83) | 1.28 (0.63) |
FEV1/FVC (SD) | 64.09 (16.61) | 62.59 (16.93) | 65.74 (16.09) | 64.84 (16.92) | 63.15 (17.24) | 66.94 (16.28) | 47.75 (14.90) | 46.57 (14.77) | 50.04 (14.89) |
Subjects with chest CT data | 6245 | 3267 | 2978 | 827 | 482 | 345 | 1502 | 975 | 527 |
Emphysema, log -950 (SD) | 0.94 (1.71) | 1.26 (1.54) | 0.60 (1.82) | 0.56 (1.80) | 0.91 (1.66) | 0.07 (1.87) | 2.42 (1.11) | 2.50 (1.05) | 2.29 (1.21) |