Fig. 2

The expression level of Slc38a6 was highly-expressed in sepsis-associated pulmonary inflammation mice. Survival rate (A) and clinical score (B, C) among control group (n = 4), 10 mg/kg LPS i.p. group (n = 8) and 20 mg/kg LPS i.p. groups (n = 8). D HE staining samples of lung tissue between control group and 20 mg/kg LPS i.p. group, the histological scores of inflammatory cell infiltration (n = 4). Slc38a6 (E), Il-1β (F), Inos (G) relative expression level in PLF among three groups (n = 4). Neutrophil and monocyte percentage in blood (H), BALF (I), PLF (J) at 24 h post injection between PBS and 20 mg/kg LPS group by FACS (n = 6). K IL-1β and TNF-α concentration in serum at 24 h post injection between PBS and 20 mg/kg LPS group by ELISA (n = 6). Data are presented as mean ± SEM of independent experiments. *p < 0.05 and **p < 0.01