Table 5 Clinical characteristics and respiratory evolution of children with periostin measured at admission for bronchiolitis according to detectable vs. non-detectable periostin
From: Nasal TSLP and periostin in infants with severe bronchiolitis and risk of asthma at 4 years of age
Detectable periostin (N = 156) N (%) | Non-detectable periostin (N = 87) N (%) | p-value | |
|---|---|---|---|
Male sex | 92(59%) | 49(56%) | 0.688 |
Age at admission < 6 months | 113(72%) | 64(75%) | 0.578 |
ICU admission | 25(16%) | 13(15%) | 0.824 |
Premature birth | 18(12%) | 8(10%) | 0.671 |
Maternal atopy | 26(18%) | 5(6%) | 0.015 |
Passive tobacco exposure | 46(34%) | 20(29%) | 0.444 |
Positive viral detection | 129(90%) | 69(85%) | 0.259 |
Viral coinfection | 42(30%) | 21(27%) | 0.691 |
RSV infection | 114(75%) | 52(64%) | 0.060 |
RV infection | 39(28%) | 21(28%) | 0.922 |
RSV + RV coinfection vs. RSV single infection | 25(22%) | 14(27%) | 0.500 |
RSV + RV coinfection vs. RV single infection | 25(64%) | 14(67%) | 0.843 |
Recurrent wheezing | 110(70%) | 68(78%) | 0.197 |
Asthma emergency visits past 12 months | 26(17%) | 23(27%) | 0.08 |
Ever use of bronchodilator | 105(69%) | 71(82%) | 0.04 |
Bronchodilator treatment past 12 months | 47(31%) | 44(52%) | 0.002 |
Asthma maintenance treatment past 12 months | 16(11%) | 18(22%) | 0.020 |
Admission for asthma | 29(19%) | 19(22%) | 0.591 |
Ever wheezing | 121(79%) | 72(84%) | 0.436 |
Wheezing in the past 12 months | 49(32%) | 41(48%) | 0.020 |
Ever asthma | 34(22%) | 17(20%) | 0.652 |
Wheezing after exercise | 20(13%) | 7(8%) | 0.248 |
Dry cough at night | 19(12%) | 16(19%) | 0.194 |