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Table 2 Multiple linear mixed regression analysis for long-term associations between adiposity indices and lung function

From: Longitudinal association between adiposity changes and lung function deterioration

 

FVC, mL

FEV1, mL

FEV1/FVC, %

Estimate (95% CI)

SE

P-value

Estimate (95% CI)

SE

P-value

Estimate (95% CI)

SE

P-value

Mena

 FMI, kg/m2

− 31.8 (− 52.3, − 11.3)

10.5

0.002

− 38.2 (− 55.4, − 21.0)

8.8

< 0.001

− 0.04 (− 0.35, 0.26)

0.15

0.775

 WHR

− 1242.2 (− 1811.3, − 672.4)

290.7

< 0.001

− 849.8 (− 1323.7, − 373.5)

241.8

< 0.001

8.30 (− 0.14, 16.77)

4.31

0.054

Womenb

 FMI, kg/m2

− 27.8 (− 38.6, − 17.0)

5.5

< 0.001

− 17.8 (− 26.9, − 8.8)

4.6

< 0.001

0.27 (0.09, 0.45)

0.09

0.004

 WHR

− 159.3 (− 452.1, 133.4)

2.7

0.902

− 69.4 (− 313.2, 174.7)

124.5

0.577

4.96 (− 0.02, 9.95)

2.54

0.051

  1. FEV1 forced expiratory volume in 1 s, FMI fat mass index, FVC forced vital capacity, SE standard error, WHR waist-to-hip ratio
  2. aMen: adjusted for age, height, residential area, follow-up duration, smoking exposure in pack-years, initial adiposity indices, interaction between age and adiposity indices, and initial lung function
  3. bNon-smoking women: adjusted for age, height, residential area, follow-up duration, initial adiposity indices, interaction between age and adiposity indices, and initial lung function