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Fig. 6 | Respiratory Research

Fig. 6

From: Impaired cell–cell communication and axon guidance because of pulmonary hypoperfusion during postnatal alveolar development

Fig. 6

KEGG pathway analysis of the DEGs during normal postnatal alveolar development and postnatal alveolar development under the influence of pulmonary hypoperfusion. A KEGG pathways of normal alveolar development. The most significant 20 KEGG pathways from the KEGG enrichment results are displayed. The abscissa is the KEGG pathway and the ordinate is the significance level of pathway enrichment. The higher the value, the greater the significance. B The KEGG pathways of normal alveolar development. Based on the KEGG enrichment results, the most significant 20 KEGG pathways were selected for the scatter plots. The abscissa is the ratio of the number of DEGs on the KEGG pathway to the total number of DEGs, the ordinate is the KEGG pathway, the size of the dots represents the number of genes annotated to the KEGG pathway, and the color from red to purple represents the significance level of KEGG pathway enrichment. C The KEGG pathway of p ostnatal alveolar development under the influence of pulmonary hypoperfusion. The most significant 20 KEGG pathways from the KEGG enrichment results are displayed. The abscissa is the KEGG pathway and the ordinate is the significance level of pathway enrichment. The higher the value, the greater the significance. D The KEGG pathways of postnatal alveolar development under the influence of pulmonary hypoperfusion. Based on the KEGG enrichment results, the most significant 20 KEGG pathways were selected for the scatter plots. The abscissa is the ratio of the number of DEGs on the KEGG pathway to the total number of DEGs, the ordinate is the KEGG pathway, the size of the dots represents the number of genes annotated to the KEGG pathway, and the color from red to purple represents the significance level of KEGG pathway enrichment. Axon guidance is not included in the list of enriched KEGG terms, and the enriched score of cell cycle terms is much higher than those of other enriched terms

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