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Fig. 5 | Respiratory Research

Fig. 5

From: Impaired cell–cell communication and axon guidance because of pulmonary hypoperfusion during postnatal alveolar development

Fig. 5

Cell–cell communication signal transduction during normal postnatal alveolar development were partly changed by cell cycle activity because of pulmonary hypoperfusion, as indicated by the GO analysis. A Based on the results of the GO enrichment analysis for normal postnatal alveolar development (S14 vs. S7), the most significant 10 terms are displayed. The abscissa is the GO term, and the ordinate is the significance level of GO term enrichment. The higher the value, the more significant the result. The different colors represent three different GO subclasses: biological process (BP), cellular component (CC), and molecular function (MF). B Based on the results of the GO enrichment analysis of normal postnatal alveolar development (S14 vs. S7), we selected the most significant 30 terms to draw scatter plots for display. The abscissa is the ratio of the number of DEGs on the GO term to the total number of DEGs, the ordinate is the GO Term, the size of the dots represents the number of genes annotated to the GO term, and the color from red to purple represents the significance level of GO term enrichment. The most enriched GO terms were associated with cell–cell communication signal transduction. C Based on the results of the GO enrichment analysis of pulmonary hypoperfusion influenced-postnatal alveolar development (P14 vs. P7), the most significant 10 terms are displayed. The abscissa is the GO term and the ordinate is the significance level of GO term enrichment. The higher the value, the more significant the result. The different colors represent three different GO subclasses: BP, CC, and MF. B Based on the results of the GO enrichment analysis of pulmonary hypoperfusion influenced-postnatal alveolar development (P14 vs. P7), we selected the most significant 30 terms to draw scatter plots for display. The abscissa is the ratio of the number of DEGs on the GO term to the total number of DEGs, the ordinate is GO Term, the size of the dots represents the number of genes annotated to the GO Term, and the color from red to purple represents the significance level of GO term enrichment. The most enriched GO terms were associated with cell cycle activity

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