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Table 3 Multivariate analysis for PRMemph

From: Principal component analysis of flow-volume curves in COPDGene to link spirometry with phenotypes of COPD

 

Entire spectrum (n = 6302)

Mild COPD (n = 567)

Moderate−severe COPD (n = 2826)

Adjusted R2 = 0.50

Adjusted R2 = 0.17

Adjusted R2 = 0.50

β

P-value

β

P-value

β

P-value

Age

1.32

 < 0.001

1.08

 < 0.001

1.40

 < 0.001

Sex

 − 0.58

 < 0.001

 − 0.70

0.01

 − 0.06

0.80

Height

0.63

 < 0.001

0.38

0.16

1.71

 < 0.001

Weight

 − 1.80

 < 0.001

 − 0.91

 < 0.001

 − 3.18

 < 0.001

Pack-years

0.17

0.09

0.35

0.05

 − 0.12

0.51

PC1

 − 4.87

 < 0.001

 − 1.55

 < 0.001

 − 2.49

 < 0.001

PC2

 − 4.34

 < 0.001

 − 1.42

 < 0.001

 − 7.28

 < 0.001

PC3

 − 0.05

0.61

0.70

0.001

2.25

 < 0.001

PC4

 − 1.37

 < 0.001

0.01

0.97

0.90

0.001

  1. COPD, Chronic Obstructive Pulmonary Disease; PC, principal component
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Respiratory Research

ISSN: 1465-993X

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