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Fig. 2 | Respiratory Research

Fig. 2

From: The main e-cigarette component vegetable glycerin enhances neutrophil migration and fibrosis in endotoxin-induced lung injury via p38 MAPK activation

Fig. 2

Neutrophil recruitment and fibrogenesis in VG-induced lung injury. VG administration increased expression of the neutrophil markers Ly6G and MPO and of the central mediator of fibrogenesis TGF-β in the lungs of mice with LPS-induced ALI. A–C Intratracheal injection of LPS increased expression of Ly6G, MPO, and TGF-β in the lungs. VG administration induced changes similar to those seen after LPS administration and enhanced the changes induced by LPS. Data sets are expressed as means ± standard deviations. *p < 0.05 vs. PBS, #p < 0.05 vs. LPS; N = 6 per group

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