Table 2 Molecules directly associated with asthma
From: Gene network analysis for identification of microRNA biomarkers for asthma
Entrez gene name | Mouse (Entrez Gene) | Log2 FC | FDR | Type(s) | Gene ID Mouse |
|---|---|---|---|---|---|
Actin alpha 2, smooth muscle | Acta2 | 1.13 | 1.39E−19 | Other | 11475 |
Actin beta | Actb | 0.82 | 2.13E−20 | Other | 11461 |
C–C motif chemokine ligand 2 | Ccl12 | 3.00 | 1.11E−58 | Cytokine | 20293 |
C–C motif chemokine receptor 3 | Ccr3 | 3.54 | 1.10E−84 | G-protein coupled receptor | 12771 |
CD86 molecule | Cd86 | 0.66 | 1.04E−09 | Transmembrane receptor | 12524 |
Cyclin dependent kinase inhibitor 1A | Cdkn1a | 0.69 | 4.50E−05 | Kinase | 12575 |
Eosinophil peroxidase | Epx | 7.02 | 9.26E−21 | Enzyme | 13861 |
Forkhead box P3 | Foxp3 | 1.00 | 6.50E−09 | Transcription regulator | 20371 |
GATA binding protein 3 | Gata3 | 0.74 | 6.19E−09 | Transcription regulator | 14462 |
Major histocompatibility complex, class II, DQ alpha 1 | H2-Aa | 1.38 | 6.01E−50 | Transmembrane receptor | 14960 |
Heme oxygenase 1 | Hmox1 | 1.81 | 2.35E−39 | Enzyme | 15368 |
Inducible T cell costimulator | Icos | 1.11 | 1.59E−09 | Transmembrane receptor | 54167 |
Interferon gamma | Ifng | 0.91 | 2.76E−03 | Cytokine | 15978 |
Interleukin 4 | Il4 | 2.95 | 8.20E−21 | Cytokine | 16189 |
Interleukin 5 | Il5 | 4.05 | 9.77E−22 | Cytokine | 16191 |
Interleukin 6 | Il6 | 1.26 | 3.79E−05 | Cytokine | 16193 |
Interleukin 10 | Il10 | 3.44 | 1.20E−24 | Cytokine | 16153 |
Interleukin 13 | Il13 | 6.84 | 2.06E−40 | Cytokine | 16163 |
Interleukin 18 | Il18 | − 1.86 | 4.28E−25 | Cytokine | 16,173 |
Interleukin 33 | Il33 | 2.00 | 8.67E−87 | Cytokine | 77125 |
Interleukin 13 receptor subunit alpha 2 | Il13ra2 | 8.17 | 7.85E−52 | Transmembrane receptor | 16165 |
Interleukin 17A | Il17a | 2.66 | 5.57E−04 | Cytokine | 16171 |
Interleukin 17 receptor B | Il17rb | 0.67 | 6.06E−04 | Transmembrane receptor | 50905 |
Interleukin 1 receptor like 1 | Il1rl1 | 1.74 | 9.85E−76 | Transmembrane receptor | 17082 |
Interleukin 2 receptor subunit alpha | Il2ra | 0.93 | 8.07E−09 | Transmembrane receptor | 16184 |
Interleukin 31 receptor A | Il31ra | 3.64 | 2.91E−23 | Transmembrane receptor | 218624 |
Interleukin 3 receptor subunit alpha | Il3ra | 0.97 | 7.54E−21 | Transmembrane receptor | 16188 |
Interleukin 9 receptor | Il9r | 1.26 | 4.96E−10 | Transmembrane receptor | 16199 |
– | mmu-miR-135b-5p | 4.01 | 0.00E+00 | Mature microRNA |  |
– | mmu-miR-148a-3p | 1.53 | 0.00E+00 | Mature microRNA |  |
– | mmu-miR-215-5p | 2.81 | 0.00E+00 | Mature microRNA |  |
Matrix metallopeptidase 9 | Mmp9 | − 0.84 | 4.85E−05 | Peptidase | 17395 |
NFKB inhibitor beta | Nfkbib | 0.63 | 2.26E−11 | Transcription regulator | 18036 |
oncostatin M | Osm | 0.61 | 4.91E−04 | Cytokine | 18413 |
Protein disulfide isomerase family A member 3 | Pdia3 | 1.03 | 4.25E−28 | Peptidase | 14827 |
Proline rich 5 | Prr5 | 1.26 | 1.77E−18 | Other | 109270 |
Prostaglandin D2 receptor 2 | Ptgdr2 | − 0.85 | 1.44E−03 | G-protein coupled receptor | 14764 |
RUNX family transcription factor 3 | Runx3 | 0.81 | 9.25E−08 | Transcription regulator | 12399 |
Spi-1 proto-oncogene | Spi1 | 1.14 | 3.33E−35 | Transcription regulator | 20375 |
Transforming growth factor beta 1 | Tgfb1 | 0.63 | 2.18E−16 | Growth factor | 21803 |
TNF receptor superfamily member 4 | Tnfrsf4 | 2.15 | 2.47E−28 | Transmembrane receptor | 22163 |
Thymic stromal lymphopoietin | Tslp | − 0.58 | 4.52E−05 | Cytokine | 53603 |
Tubulin alpha 1c | Tuba1c | 1.40 | 2.23E−48 | Other | 22146 |
Tubulin beta class I | Tubb5 | 0.63 | 4.01E−13 | Other | 22154 |
Tubulin beta 1 class VI | Tubb1 | − 1.63 | 3.65E−08 | Other | 545486 |
Tubulin beta 3 class III | Tubb3 | 1.21 | 2.11E−03 | Other | 22152 |
Vav guanine nucleotide exchange factor 1 | Vav1 | 0.91 | 1.66E−20 | Transcription regulator | 22324 |
Vitamin D receptor | Vdr | 1.40 | 4.89E−47 | Transcription regulator | 22337 |