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Fig. 1 | Respiratory Research

Fig. 1

From: Emerging roles of mechanosensitive ion channels in acute lung injury/acute respiratory distress syndrome

Fig. 1

Mechanistic models of mechanosensitive ion channels (MSCs). A Force-from-lipids model. Mechanical forces applied to a lipids bilayer can directly activate MSCs without a need for additional elements such as cytoskeleton or accessory proteins. B Force-from-tethers model. MSCs are tethered to the extracellular martrix (ECM) and/or the cytoskeleton, and the transmission of mechanical forces through a tether connecting MSCs can change the conformation of MSCs and gate these channels

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Respiratory Research

ISSN: 1465-993X

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