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Fig. 6 | Respiratory Research

Fig. 6

From: O-linked N-acetylglucosamine affects mitochondrial homeostasis by regulating Parkin-dependent mitophagy in hyperoxia-injured alveolar type II cells injury

Fig. 6

Effect of O-GlcNAc enzyme inhibitor in alveolarization of hyperoxia-exposed neonatal rats. a Hematoxylin–eosin staining (H&E) for histopathological observation of alveolar morphology (scale bars = 50 μm). b Radial alveolar counts (RAC) values in groups determined by measuring the vertical distance from the center of a bronchiole to the nearest fibrous septum or pleura. c Body weight at 14 days of each group. Data are shown as the mean ± SEM (n = 10) and were analyzed using two-way ANOVA followed by Tukey’s post-hoc tests. *P < 0.05, **P < 0.01. NO: normal air-exposed group; HO: hyperoxia-exposed group. NC: negative control group; TG: Thiamet G-treated group; OS: OSMI-1-treated group; UDP: UDP-GlcNAc-treated group

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