Table 2 Patient stratification by the presence or absence of weight loss
From: Association between weight loss and mortality in idiopathic pulmonary fibrosis
Characteristic | All (n = 71) | > 5% weight loss in 1st year (n = 21) | No weight loss in 1st year (n = 50) | P-Value |
|---|---|---|---|---|
Age (years) | 71.3 ± 9.5 | 69.9 ± 8.7 | 71.9 ± 9.8 | 0.34 |
Female Gender | 21 (29%) | 7 (33%) | 14 (28%) | 0.78 |
Weight at diagnosis (kg) | 88.6 ± 17.9 | 89.3 ± 14.1 | 88.3 ± 19.4 | 0.83 |
BMI at diagnosis | 29.8 ± 4.94 | 30.6 ± 4.11 | 29.5 ± 5.23 | 0.40 |
Smoking (any) | 50 (70%) | 15 (71%) | 35 (70%) | 0.90 |
Pulmonary rehab | 14 (18%) | 5 (24%) | 9 (16%) | 0.52 |
Antidepressant | 24 (33%) | 5 (23%) | 16 (32%) | 0.38 |
Antifibrotic (any) | 36 (51%) | 13 (62%) | 23 (46%) | 0.30 |
Nintedanib | 19 (27%) | 7 (33%) | 12 (24%) | 0.56 |
Pirfenidone | 17 (23%) | 6 (29%) | 11 (22%) | 0.55 |
FVC at diagnosis (L) | 2.9 ± 0.8 | 2.6 ± 0.8 | 3.1 ± 0.8 | 0.02* |
FVC% Predicted | 79.2 ± 19.4 | 70.5 ± 19.9 | 82.4 ± 18.3 | 0.02* |
DLCO at diagnosis (mL/min/mm Hg) | 11.6 ± 4.7 | 10.0 ± 4.5 | 12.3 ± 4.6 | 0.08 |
Reflux disease | 31 (44%) | 11 (52%) | 20 (40%) | 0.43 |
Diabetes | 13 (18%) | 5 (24%) | 8 (16%) | 0.50 |
OSA | 9 (13%) | 2 (10%) | 7 (14%) | 0.72 |
Oxygen use | 22 (31%) | 12 (57%) | 10 (20%) | 0.72 |