Table 5 Multivariate analysis of variables associated with FEV1(%) in individuals with PI*ZZ genotype in EARCO
Variables | FEV1(%) | |||||
|---|---|---|---|---|---|---|
All (n = 453) | Augmented (n = 157) | Non-augmented (n = 296) | ||||
Beta | 95% CI | Beta | 95% CI | Beta | 95% CI | |
Age | − 0.366 | − 0.543, − 0.189 | NS | – | − 0.577 | − 0.792, − 0.362 |
Sex (male) | − 10.414 | − 15.087, − 5.741 | − 13.460 | − 20.283, − 6.638 | − 8.004 | − 14.006, − 2.003 |
Smokers | NS | – | NS | – | NS | – |
Exacerbations | − 15.741 | − 20.781, − 10.701 | − 13.476 | − 20.191, − 6.761 | − 16.985 | − 23.870, − 10.100 |
Pneumonia | NS | – | NS | – | NS | – |
Blood eosinophils | NS | – | NS | – | NS | – |
Blood neutrophils | − 0.060 | − 0.092, − 0.027 | NS | – | − 1.158 | − 2.261, − 0.056 |
Serum AAT | 27.077 | 22.949, 31.205 | NS | – | NS | – |
Platelets | − 0.565 | − 0.859, − 0.125 | NS | – | − 0.068 | − 0.112, − 0.024 |
Augmentation | − 0.366 | − 0.543, − 0.189 | NS | – | NS | – |