Outcomes and risk factors with COVID-19 or influenza in hospitalized asthma patients

Respiratory Research

Table 3 Risk factors for admission to an ICU or hospital death for asthma patients by disease

	COVID-19 asthma patients n = 402 (170 events)			2018–2019 influenza period asthma patients n = 309 (74 events)			2017–2018 influenza period asthma patients n = 283 (63 events)
	OR [95% CI]	aOR [95% CI]	p value	OR [95% CI]	aOR [95% CI]	p value	OR [95% CI]	aOR [95% CI]	p value
Age ≥ 70 years	0.60 [0.40–0.89]	0.64 [0.42–0.97]	0.037	0.66 [0.39–1.12]	0.49 [0.25–0.91]	0.033	0.84 [0.48–1.47]
Female	0.39 [0.26–0.58]	0.38 [0.25–0.58]	< 0.001	0.72 [0.42 –1.26]			0.70 [0.40–1.24]
Diabetes	1.02 [0.65–1.59]			1.57 [0.88–2.77]			1.16 [0.59–2.18]
Obesity	1.48 [0.99–2.22]	1.55 [1.00–2.41]	0.049	1.11 [0.63–1.93]			2.22 [1.25–3.96]	2.22 [1.25–3.96]	0.0070
Smoking	1.73 [1.16–2.60]	1.57 [1.03–2.40]	0.035	2.92 [1.67–5.27]	2.95 [1.67–5.39]	< 0.001	1.38 [0.78–2.47]
Ischemic heart disease	1.25 [0.73–2.13]			1.16 [0.62–2.12]			1.25 [0.64–2.37]
Heart failure	1.12 [0.65–1.91]			1.49 [0.84–2.60]	2.05 [1.03–4.15]	0.040	1.72 [0.94–3.09]
Stroke	1.13 [0.54–2.37]			0.70 [0.23–1.79]			1.49 [0.55–3.65]
Chronic renal failure	1.15 [0.64–2.06]			0.78 [0.36–1.56]			1.55 [0.77–3.01]

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